DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and plat

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_002663097.1	Gene:	plat / 100320028	ZFINID:	ZDB-GENE-081104-181	Length:	578	Species:	Danio rerio

Alignment Length:	354	Identity:	98/354 - (27%)
Similarity:	144/354 - (40%)	Gaps:	67/354 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PELDAGPGKPEEKMWFHI---TDFQFDRVEGPTQPKPKPRQYPPPPMPGQPFPPPPGGFKKKENK 112
            |:.|.||       |.|:   :...::..:.|    ..||:.|.....|   |..|.     ...
Zfish   267 PDGDLGP-------WCHVYKGSQLTWELCDVP----QCPRKLPSITTLG---PRAPA-----TTN 312

  Fly   113 QRRLCEQKYSEYVERIFPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQV-DYKCGG 176
            .:.:|.|:  |....:.|........|:|.          .|.|..||:.....|.:. ::.|||
Zfish   313 NQGVCGQR--ESPSNLLPMFRIRGGQASDI----------REQPWQAAITVYLPRSKTHNFLCGG 365

  Fly   177 SLISERFVLTAAHC-TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDI 240
            .||...::|:|||| ...||.....|.:|  .....:.|...|:..:|:.:.|..|..:.|.:||
Zfish   366 VLIDSCWILSAAHCFQQRYEESRLRVVLG--RTFRLQNSSSEQIFDVEKYWIHEQYDDETYDNDI 428

  Fly   241 ALLKLEKEVEL----TEYVRPVRLWVFPE----LPT-TIAFAMGYGATSFAKPM-TNRLTNLNLT 295
            |||||:.|..:    :..|.|..|   ||    ||. |.....|||......|. :.|:....:.
Zfish   429 ALLKLKSESGICAVHSPEVLPACL---PEPNLVLPDWTECEISGYGKEEEFSPFYSERIKRGLVR 490

  Fly   296 VVPNAECNAELPPLAETPSG--VLESQICAQDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHL 358
            :.|..:|      :.|..||  |..:.:||.|.....|.|:|||||||.....||..       |
Zfish   491 LWPQDQC------VPEKLSGRLVTSNMLCAGDTRGLDDACKGDSGGPLVCQKNGRMT-------L 542

  Fly   359 IGITSYGVFC-RSSYPSVYTRVSSFLDWI 386
            :|:.|:|..| :...|.|||||:.:.:||
Zfish   543 MGLISWGDGCGKKDTPGVYTRVTKYTNWI 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	79/256 (31%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	77/254 (30%)
plat	XP_002663097.1	EGF_CA	<87..116	CDD:238011
		KR	121..204	CDD:238056
		KR	211..294	CDD:214527	7/37 (19%)
		Tryp_SPc	331..571	CDD:214473	79/267 (30%)
		Tryp_SPc	334..574	CDD:238113	81/266 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910