DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	258	Identity:	79/258 - (30%)
Similarity:	118/258 - (45%)	Gaps:	38/258 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 DADFDGRVLARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWVRIGD 205
            |....|..|.|.|..|....:..|.:.|    .||||||::|:|:|||||   .:..|..:.|||
Zfish   246 DTRIVGGQLQRQGGSPWQVLLRREDEYG----FCGGSLINQRWVITAAHC---LQQTPHHITIGD 303

  Fly   206 LD-LASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPEL--- 266
            .| :..:|   :.|.:.:|::..||:|.:..:..|||||.|...|.|..:..|..|   |:.
Zfish   304 YDKMRPDK---DEQKITVEKIIPHPHYHEYTFDSDIALLYLSSAVTLGPFASPACL---PDANLA 362

  Fly   267 -----PTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDY 326
                 |.......|:|:|.:.:..:..|..:.|.||....|      :..|...:.::..||...
Zfish   363 ERLMKPGEQGLVSGWGSTHYLQRSSRFLRKVQLPVVEQKSC------INSTEQIITDNMFCAGFL 421

  Fly   327 ILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFCRS--SYPSVYTRVSSFLDWIE 387
            :...|.|.||||||..:|..|.       :.|.|:.|:|..|.|  .| .||||:.::|.||:
Zfish   422 MEEMDACTGDSGGPFIVNYRGT-------WFLTGVVSWGERCASQGKY-GVYTRLGNYLSWIQ 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	77/251 (31%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	76/250 (30%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	76/253 (30%)
		Tryp_SPc	249..477	CDD:238113	78/255 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910