DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and masp1

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001373185.1	Gene:	masp1 / 100002060	ZFINID:	ZDB-GENE-110421-4	Length:	740	Species:	Danio rerio

Alignment Length:	429	Identity:	103/429 - (24%)
Similarity:	150/429 - (34%)	Gaps:	143/429 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LRNLSVCLISFIGLWCLSNTHTQRLPPEGRMRPLQDDSIRSPVDRDIVFPELDAGPGKPEEKMWF 66
            :.|...|..|  |:|                  |.||.:..|          ...||
Zfish   401 VNNTYTCNQS--GIW------------------LSDDGMPLP----------SCLPG-------- 427

  Fly    67 HITDFQFDRVEGPTQPKPKPRQYPPPPM----PGQPFPPPPGGFKKKENKQRRLCEQKYSEYVER 127
             :.:....|..||..|.|    ....|:    ..||||.          .|:|:
Zfish   428 -VIEGNLSRPAGPESPTP----LASTPLACGEQSQPFPA----------HQKRI----------- 466

  Fly   128 IFPNDTAVAADANDADFDGRVLARPGEYPHMAAVGFESDRGQVDYKC-------GGSLISERFVL 185
                            ..||. |.||.:|....:..|.     .|:.       .|:|:|..:::
Zfish   467 ----------------VGGRP-ASPGLFPWQVLLSVED-----VYRVPVVRWFGSGALLSPLWIV 509

  Fly   186 TAAHC-------TSIYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALL 243
            ||||.       .|:....|:.::: .|.|...::...|....:|::..||.:..:.|.:||||:
Zfish   510 TAAHVLRSHRLDLSVVPVDPEHIQV-HLGLTDVRQKHLATNRSVEKIILHPQFDPQNYNNDIALV 573

  Fly   244 KLEKEVELTEYVRPVRLWVFPE--------LPTTIAFAMGY------------GATSFAKPMTNR 288
            ||.:||.|:..||||.|   |.        .|.|:....|:            |.||.:..::..
Zfish   574 KLNQEVALSALVRPVCL---PRPGLDSQVLTPNTLGIVAGWGINAANASASSSGLTSDSSSVSEL 635

  Fly   289 LTNLNLTVVPNAECNAELPPLAETPSGVLESQICAQDYILNRDTCQGDSGGPL--QLNLPGRRRG 351
            |..:.|.||...||.|.... ......:..:..||..|...:|||.|||||..  |....||...
Zfish   636 LQYVKLPVVSQDECEASYAS-RSVNYNITGNMFCAGFYEGGQDTCLGDSGGAFVTQDGRSGRWVA 699

  Fly   352 HRIHYHLIGITSYG--VFCRSS--YPSVYTRVSSFLDWI 386
            |       |:.|:|  ..|.|.  | .|||||:::|.|:
Zfish   700 H-------GLVSWGGPEECGSQRVY-GVYTRVANYLQWL 730

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	80/281 (28%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	79/279 (28%)
masp1	NP_001373185.1	CUB	29..135	CDD:214483
		FXa_inhibition	143..181	CDD:405372
		CUB	189..294	CDD:395345
		PHA02639	<300..>425	CDD:165022	9/53 (17%)
		Sushi	301..362	CDD:395037
		Tryp_SPc	465..729	CDD:214473	80/309 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910