DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14642 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	256	Identity:	75/256 - (29%)
Similarity:	118/256 - (46%)	Gaps:	34/256 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 FDGRV----LARPGEYPHMAAVGFESDRGQVDYKCGGSLISERFVLTAAHCTSIYEAPPKWV--- 201
            |..|:    |:..|::|...::.|::     ::.||||:|:.|::||||||......|..|:
Zfish   294 FSARIVGGNLSAEGQFPWQVSLHFQN-----EHLCGGSIITSRWILTAAHCVYGIAYPMYWMVYA 353

  Fly   202 RIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYVRPVRLWVFPEL 266
            .:.:|.|.:.|      ...:|::..|..|:.|....||||:||.:.:.....|.|:.|..|.|.
Zfish   354 GLTELPLNAVK------AFAVEKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQ 412

  Fly   267 --PTTIAFAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSGVLES-QICAQDYIL 328
              ...:.:..|:|||......:......::.::.|..|:.     .|...|.|.: .|||.....
Zfish   413 FEDGKMCWISGWGATEDGGDASVSQHCASVPLISNKACSQ-----PEVYQGYLTAGMICAGYLDG 472

  Fly   329 NRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYTRVSSFLDWIEL 388
            ..|:|||||||||...       ....:.|:|.||:|..| ..:.|.||||::..|.||.|
Zfish   473 GTDSCQGDSGGPLACE-------DSSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHL 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	72/251 (29%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	71/250 (28%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845
		Tryp_SPc	298..525	CDD:238113	71/249 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910