Protein Alignment abs and PRP5

DIOPT Version :10

• Sequence 1: NP_524220.1
• Gene: abs / 40530
• FlyBaseID: FBgn0015331
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_009796.1
• Gene: PRP5 / 852539
• SGDID: S000000441
• Length: 849
• Species: Saccharomyces cerevisiae
• Alignment Length: 589
• Identity: 173/589 - (29%)
• Similarity: 274/589 - (46%)
• Gaps: 106/589 - (17%)

  Fly     4 VKRYRRSSKSSE---------EGDLDNEDYVPYVPVKERKKQHMIKLGRIVQLVSETAQPKSSSE 59
            ||..::.||.|:         ..|.|:|     :.|..|.|:|:.|                :.|
Yeast    87 VKPSKKKSKRSKVKKKISFDFSDDDDSE-----IGVSFRSKEHIQK----------------APE 130

  Fly    60 NENEDDSQGAHDVETWGRKYNISLLDQH-TELK--KIAEAK------KLSAVEKQLRE-----EE 110
            ::||.|.                 ||:. |.||  |::.:|      .:..||.||.|     :|
Yeast   131 HDNEKDP-----------------LDEFMTSLKEEKMSNSKGMYDRGDILDVEDQLFELGGTDDE 178

  Fly   111 KIMES--------IAQQKALMGVAELAKGIQYEQPI-KTAWKPPRYIREMSEEEREAVRHEL-RI 165
            .:.::        ||:.||...|.::....:..:|. |..:.....:..|||.|.|.:|..| .|
Yeast   179 DVEDNTDNSNIAKIAKLKAKKRVKQIYYSPEELEPFQKNFYIESETVSSMSEMEVEELRLSLDNI 243

  Fly   166 LVEGETPSPPIRSFREMKFPKGILNGLAAK-GIKNPTPIQVQGLPTVLAGRDLIGIAFTGSGKTL 229
            .::|.....|:..:.::......:..:..| ...:.||||.|.||.:::|||:|||:.||||||:
Yeast   244 KIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSLTPIQSQALPAIMSGRDVIGISKTGSGKTI 308

  Fly   230 VFVLPVIMFALEQEYSLPFERNE-GPYGLIICPSRELAKQTHEIIQHYSKHLQACGMPEIRSCLA 293
            .::||::.....|.   |..::| ||.|||:.|:||||.|.||.:..:::     ....|||...
Yeast   309 SYLLPLLRQVKAQR---PLSKHETGPMGLILAPTRELALQIHEEVTKFTE-----ADTSIRSVCC 365

  Fly   294 MGGLPVSEALDVISRGVHIVVATPGRLMDML---DKKILTLDMCRYLCMDEADRMIDMGFEEDVR 355
            .||..:.:.:..:.||..||||||||.:|:|   |.|:|:.....::.||||||:.|:|||..:.
Yeast   366 TGGSEMKKQITDLKRGTEIVVATPGRFIDILTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQIT 430

  Fly   356 TIFSFFKGQRQTLLFSATMPKKIQNFARSALVKPVTINVGRAGAASMNVTQQVEYVKQEAK---- 416
            .|....:..:|.:|||||.|.|:::||...|..|::|.:...|..:.||.|:......|.:
Yeast   431 QIMKTVRPDKQCVLFSATFPNKLRSFAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDN 495

  Fly   417 VVYLL------------------DCLQKTAPPVLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKD 463
            :|.|:                  ..:::.....:||...:...|.|.:.||..|:...|||.||.
Yeast   496 LVQLIHERSEFFDEVQSENDGQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKP 560

  Fly   464 QEERSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLA 528
            .:||...::.::..|..:|:.|:|.|:||:.|.|..||.|:.......|||..|||.|.:..|.|
Yeast   561 YQERLMNLEKFKREKNSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTA 625

  Fly   529 TTLI 532
            .||:
Yeast   626 ITLL 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc_DDX41	188..393	CDD:350709	81/209 (39%)
		SF2_C_DEAD	404..532	CDD:350174	41/149 (28%)
PRP5	NP_009796.1	DEADc_DDX46	244..468	CDD:350711	83/231 (36%)
		SrmB	255..707	CDD:440279	126/383 (33%)
		KH-I_PRP5_like	749..837	CDD:411902