DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment abs and AT5G51280

DIOPT Version :9

Sequence 1:	NP_524220.1	Gene:	abs / 40530	FlyBaseID:	FBgn0015331	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_199941.1	Gene:	AT5G51280 / 835202	AraportID:	AT5G51280	Length:	591	Species:	Arabidopsis thaliana

Alignment Length:	602	Identity:	346/602 - (57%)
Similarity:	440/602 - (73%)	Gaps:	25/602 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EEGDLDNEDYVPYVPVKERKKQHMIKLGRIVQLVSETAQPKSSSENENEDDSQGAHDVETWGRKY 79
            ||.|    .|:.||.|.||:   .|...:|:|      :...:||.|.|.|.:...:.:.
plant     6 EEAD----SYIEYVSVAERR---AIAAQKILQ------RKGKASELEEEADKEKLAEAKP----- 52

  Fly    80 NISLLDQHTELKKIAEAKKLSAVEKQLREEEKIMESIAQQKALMGVAELAKGIQYEQPIKTAWKP 144
              |||.|.|:||:  :..::||.|:.:.:|:::||.::.:|.||.|.||||||.|.:|:.|.|||
plant    53 --SLLVQATQLKR--DVPEVSATEQIILQEKEMMEHLSDKKTLMSVRELAKGITYTEPLLTGWKP 113

  Fly   145 PRYIREMSEEEREAVRHELRILVEGETPSPPIRSFREMKFPKGILNGLAAKGIKNPTPIQVQGLP 209
            |.:||:||.::|:.:|.:..|:|.|:...|||::|::||||:.:|:.|..|||..||||||||||
plant   114 PLHIRKMSSKQRDLIRKQWHIIVNGDDIPPPIKNFKDMKFPRPVLDTLKEKGIVQPTPIQVQGLP 178

  Fly   210 TVLAGRDLIGIAFTGSGKTLVFVLPVIMFALEQEYSLPFERNEGPYGLIICPSRELAKQTHEIIQ 274
            .:|||||:|||||||||||||||||:||.||::|..:|....|||.|||:|||||||:||:|:::
plant   179 VILAGRDMIGIAFTGSGKTLVFVLPMIMIALQEEMMMPIAAGEGPIGLIVCPSRELARQTYEVVE 243

  Fly   275 HYSKHLQACGMPEIRSCLAMGGLPVSEALDVISRGVHIVVATPGRLMDMLDKKILTLDMCRYLCM 339
            .:...|...|.|.:||.|.:||:.:...|:|:.|||||||||||||.|||.||.::||.||||.:
plant   244 QFVAPLVEAGYPPLRSLLCIGGIDMRSQLEVVKRGVHIVVATPGRLKDMLAKKKMSLDACRYLTL 308

  Fly   340 DEADRMIDMGFEEDVRTIFSFFKGQRQTLLFSATMPKKIQNFARSALVKPVTINVGRAGAASMNV 404
            |||||::|:|||:|:|.:|..||.||||||||||||.|||.|||||||||||:||||||||:::|
plant   309 DEADRLVDLGFEDDIREVFDHFKSQRQTLLFSATMPTKIQIFARSALVKPVTVNVGRAGAANLDV 373

  Fly   405 TQQVEYVKQEAKVVYLLDCLQKTAPPVLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKDQEERSR 469
            .|:|||||||||:||||:|||||:||||||.|.|.|||.||||||||||||||||||||||:|..
plant   374 IQEVEYVKQEAKIVYLLECLQKTSPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDREY 438

  Fly   470 AVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLATTLINK 534
            |:.:::.|||||||||||||||||||::|||||||||.:|||||||||||||....|:|||.|||
plant   439 AISSFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPAEIENYVHRIGRTGRCGKTGIATTFINK 503

  Fly   535 TTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQHLDLGDS--HGCTYCGGLGHRITECPKLEA 597
            ...::.||||||||.|.||.:|..|.||....|........|  .||.|||||||||.:|||||.
plant   504 NQSETTLLDLKHLLQEAKQRIPPVLAELNDPMEEAETIANASGVKGCAYCGGLGHRIRDCPKLEH 568

  Fly   598 VQNKQASNIGRRDYLSN 614
            .::...|| .|:||..:
plant   569 QKSVAISN-SRKDYFGS 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc	179..393	CDD:238167	138/213 (65%)
		DEXDc	192..397	CDD:214692	135/204 (66%)
		Helicase_C	414..523	CDD:278689	88/108 (81%)
AT5G51280	NP_199941.1	SrmB	118..>531	CDD:223587	273/412 (66%)
		DEADc_DDX41	157..362	CDD:350709	133/204 (65%)
		ZnF_C2HC	549..565	CDD:197667	12/15 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	244	1.000	Domainoid score	I565
eggNOG	1	0.900	-	-		E1_KOG0341
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9431
Inparanoid	1	1.050	669	1.000	Inparanoid score	I152
OMA	1	1.010	-	-		QHG53695
OrthoDB	1	1.010	-	-		D447398at2759
OrthoFinder	1	1.000	-	-		FOG0005487
OrthoInspector	1	1.000	-	-		otm2808
orthoMCL	1	0.900	-	-		OOG6_103442
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3903
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840