DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment abs and eIF4A

DIOPT Version :9

Sequence 1:	NP_524220.1	Gene:	abs / 40530	FlyBaseID:	FBgn0015331	Length:	619	Species:	Drosophila melanogaster
Sequence 2:	NP_001245907.1	Gene:	eIF4A / 33835	FlyBaseID:	FBgn0001942	Length:	403	Species:	Drosophila melanogaster

Alignment Length:	396	Identity:	123/396 - (31%)
Similarity:	199/396 - (50%)	Gaps:	35/396 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 SFREMKFPKGILNGLAAKGIKNPTPIQVQGLPTVLAGRDLIGIAFTGSGKTLVFVLPVIMFALEQ 242
            :|.:|...:.:|.|:...|.:.|:.||.:.:...:.|||:|..|.:|:|||..|.:.::     |
  Fly    31 NFDDMNLREELLRGIYGYGFEKPSAIQQRAIIPCVRGRDVIAQAQSGTGKTATFSIAIL-----Q 90

  Fly   243 EYSLPFERNEGPYGLIICPSRELAKQTHEIIQ---HYSK-HLQACGMPEIRSCLAMGGLPVSEAL 303
            :........:   .||:.|:||||.|...::.   .|.| |..||          :||..|.|..
  Fly    91 QIDTSIRECQ---ALILAPTRELATQIQRVVMALGEYMKVHSHAC----------IGGTNVREDA 142

  Fly   304 DVISRGVHIVVATPGRLMDMLDKKILTLDMCRYLCMDEADRMIDMGFEEDVRTIFSFFKGQRQTL 368
            .::..|.|:||.||||:.||:::|:|.....:...:||||.|:..||::.::.:|.......|.:
  Fly   143 RILESGCHVVVGTPGRVYDMINRKVLRTQYIKLFVLDEADEMLSRGFKDQIQDVFKMLPPDVQVI 207

  Fly   369 LFSATMPKKIQNFARSALVKPVTINVGRAGAASMNVTQQVEYVKQE----AKVVYLLDCLQKTAP 429
            |.|||||..:...:|..:..||:|.|.:.......:.|....||||    ..:..|.|.|..|..
  Fly   208 LLSATMPPDVLEVSRCFMRDPVSILVKKEELTLEGIKQFYVNVKQENWKLGTLCDLYDTLSITQS 272

  Fly   430 PVLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKDQEERSRAVDAYRVGKKDVLVATDVASKGLDF 494
              :||...::.||.:.:.:.:......|:||..:|.:|...:..:|.|...||:.||:.::|:|.
  Fly   273 --VIFCNTRRKVDQLTQEMSIHNFTVSAMHGDMEQRDREVIMKQFRSGSSRVLITTDLLARGIDV 335

  Fly   495 PNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLATTLINKTTEQSVLLDLK---HLLIEGKQEVP 556
            ..|..|||||:|.:.|||:|||||.||...||:|...|. ..::.:|.|::   |..||   |:|
  Fly   336 QQVSLVINYDLPSNRENYIHRIGRGGRFGRKGVAINFIT-DDDRRILKDIEQFYHTTIE---EMP 396

  Fly   557 DFLDEL 562
            ..:.:|
  Fly   397 ANIADL 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc	179..393	CDD:238167	66/217 (30%)
		DEXDc	192..397	CDD:214692	64/208 (31%)
		Helicase_C	414..523	CDD:278689	39/112 (35%)
eIF4A	NP_001245907.1	PTZ00424	6..403	CDD:185609	123/396 (31%)
		DEADc	32..232	CDD:238167	66/217 (30%)
		Helicase_C	254..358	CDD:278689	33/105 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930