Protein Alignment abs and ddx46

DIOPT Version :10

• Sequence 1: NP_524220.1
• Gene: abs / 40530
• FlyBaseID: FBgn0015331
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001019988.2
• Gene: ddx46 / 321948
• ZFINID: ZDB-GENE-030131-667
• Length: 1035
• Species: Danio rerio
• Alignment Length: 673
• Identity: 206/673 - (30%)
• Similarity: 316/673 - (46%)
• Gaps: 117/673 - (17%)

  Fly    31 KERKKQHMIKLGRIVQLVSETAQPKS-SSENENEDDSQGAHDVETWG------------------ 76
            :|::|:.|..:|.|.:.:.|..|.|. |.|::::||.:....||..|
Zfish   140 EEQRKKAMENIGEIKKELEEMKQGKKWSLEDDDDDDEEAPAPVEPDGDDEEEQDKAAEAEESERM 204

  Fly    77 -----------------------RKYNISLL----DQH-----TELKKIAEAKKL---------- 99
                                   :|:|:..:    |:.     |::..:.:.||:
Zfish   205 EEEEVGEEVDPLDAYMEEVKEEVKKFNMGTMKGANDKKGGMSVTKVVTVVKTKKMPHATKKKGEL 269

  Fly   100 -----SAVEKQLREEE---------------KIMESIAQQKALMGVAELAKGIQYEQPIKTAWKP 144
                 .|:|....|||               |::|.:..||           ||||...|..:..
Zfish   270 MENDQDAMEYSSEEEEVDLQTALTGFQTKQRKVLEPVDHQK-----------IQYEPFRKNFYVE 323

  Fly   145 PRYIREMSEEEREAVRHELR-ILVEGETPSPPIRSFREMKFPKGILNGLAAKGIKNPTPIQVQGL 208
            ...:..||.||....|.||. |.|:|:....||:::.:......:||.|.....:.|||||.|.:
Zfish   324 VPELARMSPEEVSEYRLELEGISVKGKGCPKPIKTWVQCGISMKVLNALKKHNYEKPTPIQAQAI 388

  Fly   209 PTVLAGRDLIGIAFTGSGKTLVFVLPVIMFALEQEYSLPFERNEGPYGLIICPSRELAKQTHEII 273
            |.:::||||||||.||||||:.|:||:....|:|.   |....|||..:|:.|:||||.|..:..
Zfish   389 PAIMSGRDLIGIAKTGSGKTIAFLLPMFRHILDQR---PVGEAEGPLAVIMTPTRELALQITKEC 450

  Fly   274 QHYSKHLQACGMPEIRSCLAMGGLPVSEALDVISRGVHIVVATPGRLMDML---DKKILTLDMCR 335
            :.:||.|      .:|.....||..:||.:..:.||..|:|.||||::|||   :.::..|....
Zfish   451 KKFSKSL------ALRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLGANNGRVTNLRRVT 509

  Fly   336 YLCMDEADRMIDMGFEEDVRTIFSFFKGQRQTLLFSATMPKKIQNFARSALVKPVTINVGRAGAA 400
            |:.:||||||.|||||..|..|....:..|||::||||.|:.::..||..|.|||.:.||.....
Zfish   510 YVVIDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRTMEALARRILSKPVEVQVGGRSVV 574

  Fly   401 SMNVTQQVEYVKQEAKVVYLLDCL--QKTAPPVLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKD 463
            ..:|.|.|..:::|.|.:.||:.|  .:....|:||.:|::..|.:.:.|:......:::|||.|
Zfish   575 CSDVEQHVIVIEEEKKFLKLLEILGHYQEKGSVIIFVDKQEHADGLLKDLMKASYPCMSLHGGID 639

  Fly   464 QEERSRAVDAYRVGKKDVLVATDVASKGLDFPNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLA 528
            |.:|...::.::.|...:||||.||::|||...:..|:||..|:..|:||||.|||||:..||.|
Zfish   640 QYDRDSIINDFKNGACRLLVATSVAARGLDVKQLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYA 704

  Fly   529 TTLINKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPETEHQHLDLG----DSHGCTYCGGLGHRI 589
            .|.|.:...:.....||.|.:.| ..||..|::|....:.|....|    .|.|.:   |.|.:.
Zfish   705 YTFITEGQARYSGDILKALELSG-SSVPAELEQLWTNFKEQQKAEGKIIKSSSGFS---GKGFKF 765

  Fly   590 TECPKLEAVQNK--QASNIGRRD 610
            .|.....|.:.|  |.:.:|..|
Zfish   766 DETEHALANERKKLQKAALGLHD 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc_DDX41	188..393	CDD:350709	88/207 (43%)
		SF2_C_DEAD	404..532	CDD:350174	48/129 (37%)
ddx46	NP_001019988.2	Q motif	357..385		7/27 (26%)
		DEAD box	514..517		2/2 (100%)