Protein Alignment abs and Ddx42

DIOPT Version :10

• Sequence 1: NP_524220.1
• Gene: abs / 40530
• FlyBaseID: FBgn0015331
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001100529.1
• Gene: Ddx42 / 303607
• RGDID: 1304909
• Length: 929
• Species: Rattus norvegicus
• Alignment Length: 646
• Identity: 211/646 - (32%)
• Similarity: 320/646 - (49%)
• Gaps: 82/646 - (12%)

  Fly    15 EEGDLDNEDYVPYVPVKERKKQHMIKLGRIVQLVSETAQPKSSSENEN-------EDDSQGAHDV 72
            ||.|..|.| :||:|.:....:...:           ::|..|..:::       |.:.|.|.|:
  Rat    79 EEEDSSNVD-LPYIPAENSPTRQQFR-----------SKPADSDSDDDPLEAFMAEVEDQAARDM 131

  Fly    73 ETWGRK----YNISLL--------DQHTELKKIAEAKKLSAVEKQLREEEKIME------SIAQQ 119
            :....|    .|:..:        ||....:.:||......|::   |||..:|      .||..
  Rat   132 KRLEEKDKERKNVKGIRDDIEEEDDQEAYFRYMAENPTAGVVQE---EEEDNLEYDSDGNPIAPS 193

  Fly   120 KALMGVAELAKGIQYEQP--IKTAWKPPRYIREMSEEEREAVRHELRILVEGETPSPPIRSFREM 182
            |.::.........:.:.|  .|..:.....|..::.::...:||:|.:.|.|..|..|..||...
  Rat   194 KKIIDPLPPIDHSEIDYPPFEKNFYNEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHF 258

  Fly   183 KFPKGILNGLAAKGIKNPTPIQVQGLPTVLAGRDLIGIAFTGSGKTLVFVLPVIMFALEQEYSLP 247
            .|.:.:::.:.......|||||.||:|..|:|||:||||.||||||..|:.|:::..::|:   .
  Rat   259 GFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQK---E 320

  Fly   248 FERNEGPYGLIICPSRELAKQTHEIIQHYSKHLQACGMPEIRSCLAMGGLPVSEALDVISRGVHI 312
            .|..:||..:|:||:|||.:|.|...:.:.|..      .:||....||..:.|....:..|..|
  Rat   321 LEPGDGPIAVIVCPTRELCQQIHAECKRFGKAY------NLRSVAVYGGGSMWEQAKALQEGAEI 379

  Fly   313 VVATPGRLMDMLDKKILTLDMCRYLCMDEADRMIDMGFEEDVRTIFSFFKGQRQTLLFSATMPKK 377
            ||.|||||:|.:.||...|....||..||||||.|||||..||:|.|..:..|||||||||..||
  Rat   380 VVCTPGRLIDHVKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKK 444

  Fly   378 IQNFARSALVKPVTINVGRAGAASMNVTQQVEYVKQ-EAKVVYLLDCLQK--TAPPVLIFAEKKQ 439
            |:..||..|:.|:.:..|..|.|:.:|||.||.:.. .:|..:|...|.:  ::..||:|..||.
  Rat   445 IEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKKA 509

  Fly   440 DVDCIHEYLLLKGVEAVAIHGGKDQEERSRAVDAYRVGKKD--VLVATDVASKGLDFPNVQHVIN 502
            :.:.:...|..:|.....:||..||.||::.:..::  |||  ||||||||::|||.|:::.|||
  Rat   510 NAEELANNLKQEGHNLGLLHGDMDQSERNKVILDFK--KKDIPVLVATDVAARGLDIPSIKTVIN 572

  Fly   503 YDMPDDIENYVHRIGRTGRSNTKGLATTLINKTTEQSVLLDLKHLLIEGKQEVPDFLDELAPET- 566
            ||:..||:.:.||||||||:..||:|.||:. ..:.:...||...|....|.|...|.:||.:.
  Rat   573 YDVARDIDTHTHRIGRTGRAGEKGVAYTLLT-PKDSNFAGDLVRNLEGANQHVSKELLDLAMQNA 636

  Fly   567 ----------EHQHLDLGDSHGCTYCGGLGHRITECPKLEAVQNKQASNIGRRDYLSNTAA 617
                      :.:.|::|.       ||||:|  |.|.|.:..:.:.||   .:.:||..|
  Rat   637 WFRKSRFKGGKGKKLNIGG-------GGLGYR--ERPGLGSENSDRGSN---NNVMSNYEA 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc_DDX41	188..393	CDD:350709	88/204 (43%)
		SF2_C_DEAD	404..532	CDD:350174	55/132 (42%)
Ddx42	NP_001100529.1	SrmB	254..677	CDD:440279	170/446 (38%)
		dermokine	<644..>889	CDD:455732	15/54 (28%)