Protein Alignment abs and Ddx46

DIOPT Version :10

• Sequence 1: NP_524220.1
• Gene: abs / 40530
• FlyBaseID: FBgn0015331
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001268984.1
• Gene: Ddx46 / 212880
• MGIID: 1920895
• Length: 1032
• Species: Mus musculus
• Alignment Length: 653
• Identity: 203/653 - (31%)
• Similarity: 323/653 - (49%)
• Gaps: 80/653 - (12%)

  Fly    31 KERKKQHMIKLGRIVQLVSETAQPKSSSENENEDDSQGAHDVETWG------------------- 76
            :|::|:.|..:|.:.:.:.|..|.|..|..:::||.....:.|..|
Mouse   172 EEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGTEMEDEELDPLDAYMEEVK 236

  Fly    77 ---RKYNI------------------SLLDQHTELKKIAEAKK---------LSAVEKQLREEEK 111
               :|:|:                  .::...|..|.:.:|.|         ..|:|....|||.
Mouse   237 EEVKKFNMRSVKGGAGNEKKSGPTVTKVVTVVTTKKAVVDADKKKGELMENDQDAMEYSSEEEEV 301

  Fly   112 IMESI-----AQQKALMGVAELAKGIQYEQPIKTAWKPPRYIREMSEEEREAVRHELR-ILVEGE 170
            .:::.     .:|:.|:...:..| |:||...|..:.....:.:||:||....|.|:. |.|:|:
Mouse   302 DLQTALTGYQTKQRKLLEPVDHGK-IEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGK 365

  Fly   171 TPSPPIRSFREMKFPKGILNGLAAKGIKNPTPIQVQGLPTVLAGRDLIGIAFTGSGKTLVFVLPV 235
            ....||:|:.:......|||.|...|.:.|||||.|.:|.:::||||||||.||||||:.|:||:
Mouse   366 GCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPM 430

  Fly   236 IMFALEQEYSLPFERNEGPYGLIICPSRELAKQTHEIIQHYSKHLQACGMPEIRSCLAMGGLPVS 300
            ....::|.   ..|..|||..:|:.|:||||.|..:..:.:||.|      .:|.....||..:|
Mouse   431 FRHIMDQR---SLEEGEGPIAVIMTPTRELALQITKECKKFSKTL------GLRVVCVYGGTGIS 486

  Fly   301 EALDVISRGVHIVVATPGRLMDML---DKKILTLDMCRYLCMDEADRMIDMGFEEDVRTIFSFFK 362
            |.:..:.||..|:|.||||::|||   ..::..|....|:.:||||||.|||||..|..|....:
Mouse   487 EQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVR 551

  Fly   363 GQRQTLLFSATMPKKIQNFARSALVKPVTINVGRAGAASMNVTQQVEYVKQEAKVVYLLDCL--Q 425
            ..|||::||||.|:.::..||..|.||:.:.||.......:|.|||..:::|.|.:.||:.|  .
Mouse   552 PDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHY 616

  Fly   426 KTAPPVLIFAEKKQDVDCIHEYLLLKGVEAVAIHGGKDQEERSRAVDAYRVGKKDVLVATDVASK 490
            :.:..|:||.:|::..|.:.:.|:......:::|||.||.:|...::.::.|...:||||.||::
Mouse   617 QESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAAR 681

  Fly   491 GLDFPNVQHVINYDMPDDIENYVHRIGRTGRSNTKGLATTLINKTTEQSVLLDLKHLLIEGKQEV 555
            |||..::..|:||..|:..|:||||.|||||:..||.|.|.|.:...:.....:|.|.:.|....
Mouse   682 GLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVP 746

  Fly   556 PDFLDELAPETEHQHLDLG----DSHGCTYCGGLGHRITECPKLEAVQNK--QASNIGRRDYLSN 614
            || |::|..:.:.|....|    .|.|.:   |.|.:..|..:..|.:.|  |.:.:|.:|....
Mouse   747 PD-LEKLWSDFKDQQKAEGKIIKKSSGFS---GKGFKFDETEQALANERKKLQKAALGLQDSDDE 807

  Fly   615 TAA 617
            .||
Mouse   808 DAA 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
abs	NP_524220.1	DEADc_DDX41	188..393	CDD:350709	88/207 (43%)
		SF2_C_DEAD	404..532	CDD:350174	49/129 (38%)
Ddx46	NP_001268984.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..227		12/54 (22%)
		DEADc_DDX46	361..582	CDD:350711	93/229 (41%)
		Q motif	372..400		10/27 (37%)
		SrmB	378..793	CDD:440279	155/427 (36%)
		DEAD box	529..532		2/2 (100%)
		KH-I_DDX46	929..1031	CDD:411901