| Sequence 1: | NP_000419.1 | Gene: | LTBP2 / 4053 | HGNCID: | 6715 | Length: | 1821 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001137905.1 | Gene: | frac / 38850 | FlyBaseID: | FBgn0035798 | Length: | 1618 | Species: | Drosophila melanogaster |
| Alignment Length: | 1270 | Identity: | 344/1270 - (27%) |
|---|---|---|---|
| Similarity: | 472/1270 - (37%) | Gaps: | 387/1270 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Human 734 SSDIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAGQVT 798
Human 799 TS-----VTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTP----GIDRCAAGATN 854
Human 855 VCGP--GTCVNL------PDG----YRCVCSPGYQLHPSQ-AYCTDDNECLRDPCKGKGRCINRV 906
Human 907 GSYSCFCYPGYTLATSGATQECQDINECEQPGVCSG--GQCTNTEGSYHC--------------- 954
Human 955 ---------------------ECDQGYIMVRKG-HCQDINECRHPG--------TCPDGRCVNSP 989
Human 990 GSYTCLACEEGY---RGQSG----SCVDV-NECLTPGVCAHGKCTNL-EGSFRCSCEQGYEVTSD 1045
Human 1046 EKGCQDVDE--CASR---ASCPTGLCLNTEG--SFACSACENGYWVNEDGTACEDLDECAFPGVC 1103
Human 1104 PSGVCTNTAGSFSCK--------------------------------------DCDGGYRPSPLG 1130
Human 1131 DSCEDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQL--ANGT--VCEDVNECMGEEH-CAPHG 1190
Human 1191 ECLNSHGSFFCLCAPGF--------------------VSAE--GGTSCQDVDECATTDPCVGGHC 1233
Human 1234 VNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPN 1298
Human 1299 G-DCIDIDECAND-TMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALC 1361
Human 1362 ENVEGSFLCLCASDLEEYDAQEGHCRPRG----AGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAP 1422
Human 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSAEFSEICPSGKGYIPVEGAWTFGQTMYTDAD 1487
Human 1488 ECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCEDHDEC-QD-LACENGECVNTEGSFH 1550
Human 1551 C-FCSPPLTLDLSQQRCMNSTS----STEDLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECC 1610
Human 1611 CQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFRPGYEYGPGPDDLHYSIYGPDGAP 1675
Human 1676 FYNYLGPEDTVPEPAFPNTAGHSADRTPILESPLQPSELQPHYVA-----SHPEPPAGFEGL-QA 1734
Human 1735 EECGILNGCENGRCVRVREGYTCDC---FEGFQLDAAHMACVDVNE--------CDDL----NG- 1783
Human 1784 --PAVLCVHG------YCENTEGSYRCHCSPGYVA 1810 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LTBP2 | NP_000419.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 38..58 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 81..165 | ||||
| Heparin-binding | 94..115 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 229..339 | ||||
| Heparin-binding | 232..249 | ||||
| Heparin-binding | 344..354 | ||||
| Cell attachment site. /evidence=ECO:0000255 | 375..377 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 510..544 | ||||
| EGF_CA | 622..>651 | CDD:214542 | |||
| TB | 683..719 | CDD:279073 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 744..772 | 6/27 (22%) | |||
| EGF_CA | 887..918 | CDD:214542 | 11/30 (37%) | ||
| EGF_CA | 930..>960 | CDD:214542 | 15/67 (22%) | ||
| EGF_CA | 970..1005 | CDD:238011 | 16/45 (36%) | ||
| EGF_CA | 1010..1041 | CDD:214542 | 15/32 (47%) | ||
| EGF_CA | 1051..1091 | CDD:284955 | 14/46 (30%) | ||
| EGF_CA | 1093..1133 | CDD:284955 | 16/77 (21%) | ||
| EGF_CA | 1135..1175 | CDD:214542 | 16/43 (37%) | ||
| EGF_CA | 1176..1217 | CDD:214542 | 16/63 (25%) | ||
| EGF_CA | 1218..1257 | CDD:284955 | 12/38 (32%) | ||
| EGF_CA | 1303..1335 | CDD:238011 | 13/32 (41%) | ||
| TB | 1423..1458 | CDD:279073 | 5/34 (15%) | ||
| EGF_CA | 1485..1518 | CDD:214542 | 14/32 (44%) | ||
| TB | 1595..1630 | CDD:279073 | 7/34 (21%) | ||
| C-terminal domain. /evidence=ECO:0000269|PubMed:17293099 | 1639..1821 | 43/202 (21%) | |||
| EGF_CA | 1774..>1808 | CDD:214542 | 12/54 (22%) | ||
| frac | NP_001137905.1 | FXa_inhibition | 296..331 | CDD:291342 | 13/36 (36%) |
| cEGF | 396..415 | CDD:289433 | 7/18 (39%) | ||
| FXa_inhibition | 425..458 | CDD:291342 | 11/34 (32%) | ||
| FXa_inhibition | 476..505 | CDD:291342 | 15/29 (52%) | ||
| vWFA | <550..586 | CDD:294047 | 12/35 (34%) | ||
| FXa_inhibition | 596..630 | CDD:291342 | 5/33 (15%) | ||
| FXa_inhibition | 636..>664 | CDD:291342 | 10/28 (36%) | ||
| EGF_CA | 676..715 | CDD:284955 | 14/38 (37%) | ||
| FXa_inhibition | 745..780 | CDD:291342 | 9/34 (26%) | ||
| FXa_inhibition | 786..821 | CDD:291342 | 13/38 (34%) | ||
| FXa_inhibition | 827..862 | CDD:291342 | 10/36 (28%) | ||
| FXa_inhibition | 874..904 | CDD:291342 | 9/44 (20%) | ||
| FXa_inhibition | 945..980 | CDD:291342 | 13/36 (36%) | ||
| CCP | 1110..1170 | CDD:153056 | 14/66 (21%) | ||
| CCP | 1183..1235 | CDD:153056 | 13/46 (28%) | ||
| DUF5011 | 1468..1536 | CDD:295940 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D4721at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR24034 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 3.020 | |||||