DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14641 and MRN1

DIOPT Version :9

Sequence 1:	NP_649440.3	Gene:	CG14641 / 40529	FlyBaseID:	FBgn0037220	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_015140.1	Gene:	MRN1 / 855917	SGDID:	S000006105	Length:	612	Species:	Saccharomyces cerevisiae

Alignment Length:	203	Identity:	45/203 - (22%)
Similarity:	79/203 - (38%)	Gaps:	37/203 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   166 SFWVKGECKRGEECPYRHDKPNEPDDPLCEQNIKDRYYGRNDPVAEKIMKRAASLPTLEPP---- 226
            :|.:..|........|.:::.:....|..::|..    ..:|.::..||..|.::.....|
Yeast   126 NFEIDNEVVHNNNRYYEYERSSNEVSPFDDENPN----VLSDGMSPTIMATATAVTNANAPLPVN 186

  Fly   227 ----EDRNIT-----TLYVGNLPEEITEPELRDQFYQFGEIRSIALVPRQQCAFVQYTKRNAAEL 282
                ...|.|     |:|:||:|..::..||.|. .:.|.:..:.::|.:.||||.:...:||.|
Yeast   187 AQANNPLNFTSAPSRTVYLGNVPPNLSVKELLDH-VRSGVVEDVKIIPEKMCAFVSFIDESAALL 250

  Fly   283 -AAERTFNKLVIQGRKVSIKWAHSQAKQGTAAKTDRRFDLAGIPPPSAKPNDYF----------N 336
             .::....:|.|..|.:.|.|       |...:.| ....|.|....|..|.|.          :
Yeast   251 FHSDAILKRLNIGDRDIKIGW-------GKPTRID-PIVAARISTDGATRNVYIGRMTIEGEESH 307

  Fly   337 LRQEQINV 344
            |.:||:.|
Yeast   308 LSEEQLRV 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14641	NP_649440.3	ZnF_C3H1	159..185	CDD:214632	3/18 (17%)
		RRM	186..>309	CDD:223796	31/136 (23%)
		RRM_RBM22	231..304	CDD:240670	23/78 (29%)
MRN1	NP_015140.1	RRM1_MRN1	200..273	CDD:240964	22/80 (28%)
		RRM2_MRN1	289..372	CDD:409943	7/27 (26%)
		RRM3_MRN1	430..503	CDD:240965
		RRM_SF	519..606	CDD:418427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14089
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100