DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14641 and MAC5C

DIOPT Version :9

Sequence 1:	NP_649440.3	Gene:	CG14641 / 40529	FlyBaseID:	FBgn0037220	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_196323.1	Gene:	MAC5C / 830597	AraportID:	AT5G07060	Length:	363	Species:	Arabidopsis thaliana

Alignment Length:	413	Identity:	163/413 - (39%)
Similarity:	219/413 - (53%)	Gaps:	81/413 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 YNRQNWEDAEFPILCQTCLGDNPYVRMIKERFGKECKICTRPFTIFRWCPGARMRFKKTEICQTC 74
            :....||.|:|||.|::|.|||||:||.:..:.||||||:||||.|||.||...|||||||||||
plant     6 HGADGWESADFPITCESCFGDNPYMRMTRADYDKECKICSRPFTAFRWRPGRNARFKKTEICQTC 70

  Fly    75 ARLKNVCQTCLLDLEYGLPIQVRDAALKVAD--NMPQSDVNKEYYIQNIDAQLQDGDGTEAAGAV 137
            ::||||||.|||||.:|||:||||:||.:..  ::|.|.||:||:....|.:.:.|...|:  :.
plant    71 SKLKNVCQVCLLDLGFGLPVQVRDSALNINSHYSVPMSHVNREYFADEHDPKTRAGLDYES--SF 133

  Fly   138 GRSLAANEMLSKLARTAPYYKRNRPHICSFWVKGECKRGEECPYRHDKPNEPDDPLCEQNIKDRY 202
            |: :..|:.:.||.|..|.|::|||.||||:..|:||||.||.:||:.|...:  |..|||:|||
plant   134 GK-MQPNDTILKLQRRTPSYEKNRPKICSFYTIGQCKRGAECSFRHEMPETGE--LSHQNIRDRY 195

  Fly   203 YGRNDPVAEKIMKRAASLPTLEPPEDRNITTLYVGNLPEEITEPELRDQFYQFGEIRSIALVP-- 265
            |..|||||.|::::|..:.|||||||.:|.|||||.|...|.|.::.|.||.:||:.||.::.
plant   196 YSVNDPVAMKLLRKAGEMGTLEPPEDESIKTLYVGGLNSRIFEQDIHDHFYAYGEMESIRVMAED 260

  Fly   266 ---------RQQCAFVQYTKRNAAELAAERTFNKLVIQGRKVSIKWAHSQAKQGTAAKTDRRFDL 321
                     :||...:.:|              .|:.|.:.     .|||.:|....
plant   261 GKYDQSGSNQQQQGSIAHT--------------GLISQQQN-----QHSQMQQYYMQ-------- 298

  Fly   322 AGIPPPSAKPNDYFNLRQEQINVMPAGMKLHQLPSNLVPASAYQMYGQPTYAAPYGNATSTALSS 386
               |||   ||:|                           |.|.........|.:....|...|:
plant   299 ---PPP---PNEY---------------------------SHYPSMDTQRMGAAFSTQESDGSST 330

  Fly   387 SGVN--LDSISIPPPPGQVPYPS 407
            |..|  ..|.|.|.||.| |||:
plant   331 SENNRAYSSYSYPMPPHQ-PYPT 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14641	NP_649440.3	ZnF_C3H1	159..185	CDD:214632	16/25 (64%)
		RRM	186..>309	CDD:223796	47/133 (35%)
		RRM_RBM22	231..304	CDD:240670	21/83 (25%)
MAC5C	NP_196323.1	ZnF_C3H1	154..178	CDD:214632	14/23 (61%)
MAC5C	NP_196323.1	RRM_SF	224..>259	CDD:302621	16/34 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	253	1.000	Domainoid score	I512
eggNOG	1	0.900	-	-		E1_KOG0153
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	356	1.000	Inparanoid score	I603
OMA	1	1.010	-	-		QHG54734
OrthoDB	1	1.010	-	-		D1272857at2759
OrthoFinder	1	1.000	-	-		FOG0003246
OrthoInspector	1	1.000	-	-		otm2590
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2658
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.940