DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment aux and JAC1

DIOPT Version :9

Sequence 1:	NP_649438.1	Gene:	aux / 40527	FlyBaseID:	FBgn0037218	Length:	1165	Species:	Drosophila melanogaster
Sequence 2:	NP_565101.1	Gene:	JAC1 / 843847	AraportID:	AT1G75100	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	589	Identity:	122/589 - (20%)
Similarity:	208/589 - (35%)	Gaps:	161/589 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   689 FTNQD-LDDLPDPEQVTPRFCVSLSLAVTDSE-SPPSHKPP-----------WMPAKPKRSPAAL 740
            ||..| .||:         |.|:.|.::..|. ..|:|||.           .:|||....|...
plant    94 FTTDDFFDDI---------FRVNESSSLPGSRILSPAHKPESSSGTSSPSQFSLPAKATEIPTFN 149

  Fly   741 FSSDLEYAEMLDNFVTKPSTRSSPPPGARKSDRVSSPLVLPD---------VTETAHELPSPM-- 794
            .::.....:..:...:.|.:|:|     .|:|.||:.....|         ||....:....:
plant   150 LAATRSLNKNKETVSSSPLSRTS-----SKADVVSTAKSYSDDCDDPPQVFVTGKGRQFHFSIYK 209

  Fly   795 -PEPSPPIDLLNLNQQPSDVPAADPLTSAKPSTD----ASFDLLGAFGDDDSTGIGSAPIPDI-- 852
             |....|:.:...::..|...|.:  |:..|.:|    :..:.||...:.|... |.:.:.|:
plant   210 WPNKGVPVVIWGSSRLSSMSKAEE--TTPVPLSDYRKTSVVEKLGKNEEGDGKS-GLSGLKDVKK 271

  Fly   853 --LPPPPLQQPQPKINND--PFDIFGSVDQGGVPSMKP----SGFPPFVGSLPTFVAQPAATTNP 909
              |..|.:|..:.|...|  ....|..|.:....::||    .....|.|     |::....|..
plant   272 TSLKRPGVQTKEEKTETDLKSEQAFFGVSKAREANVKPLDSVESEQAFSG-----VSKAHEATTV 331

  Fly   910 SPTHPARASAD-----PFANIADLATGLNLNFN-----------RSTLSGKSPVNTSPQPTQFSS 958
            .|.|......|     ...:..::..|.:...|           :.:...||.:::||.|.:.|.
plant   332 KPLHSIFHEEDERQDEKIVSEREVRKGKSKAKNTRSFTEDSRTKKKSQGTKSSLDSSPIPDKSSF 396

  Fly   959 PTHKPSP----------------------------SSQPQATFMHTPPTPQT------------- 982
            .:...:|                            .|..|::......||:|
plant   397 ASSSAAPEVGKDGVKGKVSDFVKIFSKGASVGAGGESLGQSSRWRAKETPKTDIIHDGSNAKETV 461

  Fly   983 -LPSTSSIRTPTQPQAVPAQSRPDYSRLHFDS--------------QKAAQQPGTGGSKNSDI-- 1030
             :|......||..| |:....:|..|....||              |:..|:|.|..:.:.||
plant   462 NIPDQQKKSTPDIP-AMNRDQKPSQSTQKKDSDRESMNYKAPGDTVQEERQEPSTTHTTSEDIDE 525

  Fly  1031 -------FADILGQQGYSFGSKMNQCPRSINEMRKEDLFKDMDPKKVRIMEWTDGKKNNIRALLC 1088
                   ..||...:     :||.:..:...|:      |::|.|   |.:|:.||..|||:||.
plant   526 PFHVNFDVEDITQDE-----NKMEEANKDAEEI------KNIDAK---IRKWSSGKSGNIRSLLS 576

  Fly  1089 SMHTVLWDNAKWQRCEMSTMVTPTEVKKAYRRACLAVHPDK---HNGTENEE-IAKLIFMELNNA 1149
            ::..:||..:.|:...:..|:....|:|:|:||.|.:||||   ...:.|:: :|:.:|..|..|
plant   577 TLQYILWSGSGWKPVPLMDMIEGNAVRKSYQRALLILHPDKLQQKGASANQKYMAEKVFELLQEA 641

  Fly  1150 WTDF 1153
            |..|
plant   642 WDHF 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	PKc_like	49..326	CDD:304357
		S_TKc	51..317	CDD:214567
		PTEN_C2	581..711	CDD:287393	7/22 (32%)
		DnaJ	<1110..1150	CDD:197617	14/43 (33%)
JAC1	NP_565101.1	PTZ00121	<230..383	CDD:173412	27/160 (17%)
JAC1	NP_565101.1	DnaJ	<602..643	CDD:197617	15/40 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0431
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001565
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23172
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000