Protein Alignment aux and PEN3

DIOPT Version :10

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: NP_566929.1
• Gene: PEN3 / 824173
• AraportID: AT3G50110
• Length: 632
• Species: Arabidopsis thaliana
• Alignment Length: 602
• Identity: 136/602 - (22%)
• Similarity: 214/602 - (35%)
• Gaps: 149/602 - (24%)

  Fly   335 DLHIMPIESLPAESP------------LKS---------------SAYSEVYTEPLSAAIP---S 369
            |:...|..|.|.|||            .||               ||::. :|..|...:|   |
plant    78 DIVPCPPGSSPRESPPSIFSSSGLSSWAKSFKFQQQDPNRTDSGMSAFTR-FTSELGLHLPTKGS 141

  Fly   370 SYNGHGSLLSSLRGGA-GTLLKNIKDTSTKVMQTMQ----QSLARN---------DLDISHITSR 420
            ...|.....::..||| .:|.|.:.|:|...::.||    ..:::|         |||:::||..
plant   142 EEVGDSRSSNTQVGGAFESLTKAVVDSSRGAVKAMQVKARHIVSQNKRRYQEGEFDLDMTYITEN 206

  Fly   421 ILVMPCP----SDG----FESTYKTNNIEDVRLSLESRFVPQKLSIYNFGQRTEPRLPPPVRTVE 477
            |:.|..|    |.|    ||..|: |::|:|....|:.. ..|..:||.   ...||....|.
plant   207 IIAMGFPAGDISSGLFGFFEGLYR-NHMEEVIKFFETHH-KDKYKVYNL---CSERLYDASRF-- 264

  Fly   478 AGSVYGCP--QAHAPNLQGLFTVSADMYNFLNADPKSVVIVQTGDSGGCTAATVICALLMYADLL 540
            .|.|...|  ..:.|.:|.:.:.....|.:|..|.::||:|.. .:|......:||.||:|....
plant   265 EGKVASFPFDDHNCPPIQLIPSFCQSAYTWLKEDIQNVVVVHC-KAGMARTGLMICCLLLYLKFF 328

  Fly   541 REPEDAVQVFAVKR---HTINLRPSEFRYLYYFGDILRP-TPLLPHYKNTTLVSLSCQPVPRMTK 601
            ...|:|:..:..||   ....:.||:.||:.|:..:... ...:|..:...|...      |:..
plant   329 PTAEEAIDYYNQKRCLDGKALVLPSQIRYVKYYERVQNQFDGKVPPERRCMLRGF------RLIN 387

  Fly   602 ARDGCRIYMEVYCNGNLLLSTLQDYEKMRLYQAGPGK--IVLPINLTACGDVTVVLFHARKGMVR 664
            .....|..:.:..:.::|.|| :.::|.:  ..||..  |..|..     .|.|.......|:..
plant   388 CPYWIRPAITISNHTDILFST-KKHQKTK--DLGPEDFWIKAPKK-----GVVVFAIPGEAGLTE 444

  Fly   665 PQGLKICQFQFNTG-FIPEPETLIT-----FTNQDLDDLPDPEQVTPRFCVSLSLAVTDSESPPS 723
            ..|.....||.:.| |.....|.:|     ....|.|.....:...|.|.|.:.:...|:..|..
plant   445 LAGDFKIHFQDSDGDFYCWLNTTLTDNRTMLKGSDFDGFDKRKLPAPGFHVEIVMIEPDNSQPTK 509

  Fly   724 HKPPWMPAKPKRSPAA-------------LFS-SDLEYAEMLDNFVTKPSTRSS----------- 763
            .|......:.:.|.:|             :|| ||.|......::.|...|.||
plant   510 SKSDSTQQQSQSSSSADSSKLKSNEKDDDVFSDSDGEEEGNSQSYSTNEKTASSMHTTSKPHQIN 574

  Fly   764 -PP----PGARKSDRVSSPLVLPDVTETAHELPSPMPEPSPPIDLLNLNQQPSDVPAADPLTSAK 823
             ||    |.|.:|...||        .:.|..|.|           |.:...||:.|.
plant   575 EPPKRDDPSANRSVTSSS--------SSGHYNPIP-----------NNSLAVSDIKAI------- 613

  Fly   824 PSTDASFDLLGAFGDDD 840
             :.|||   :.:|||::
plant   614 -AADAS---VFSFGDEE 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	Protein Kinases, catalytic domain	49..326	CDD:473864
		PTP_auxilin-like	404..573	CDD:350361	51/194 (26%)
		PTEN_C2	581..711	CDD:463081	27/137 (20%)
		PHA03247	<698..1037	CDD:223021	37/173 (21%)
		Herpes_BLLF1	<882..>999	CDD:282904
		DnaJ	<1110..1150	CDD:99751
PEN3	NP_566929.1	PTP_PTEN	199..363	CDD:350359	47/171 (27%)