Protein Alignment aux and TPTE

DIOPT Version :9

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: NP_954870.3
• Gene: TPTE / 7179
• HGNCID: 12023
• Length: 551
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 72/317 - (22%)
• Similarity: 134/317 - (42%)
• Gaps: 64/317 - (20%)

  Fly   411 DLDISHITSRILVMPCPSDGFESTYKTNNIEDVRLSLESRFVPQK----LSIYNFGQRTEPRLPP 471
            |||::::|.||:.|..||.|.:|.|: |.|::|     .||:.:|    ..:||.  .:|....|
Human   236 DLDLTYVTERIIAMSFPSSGRQSFYR-NPIKEV-----VRFLDKKHRNHYRVYNL--CSERAYDP 292

  Fly   472 P------VRTVEAGSVYGCPQAHAPNLQGLFTVSADMYNFLNADPKSVVIVQTGDSGGC-TAATV 529
            .      ||.:       ....:.|.|..:...:.::..::..|.:::|.:..  .||. ...|:
Human   293 KHFHNRVVRIM-------IDDHNVPTLHQMVVFTKEVNEWMAQDLENIVAIHC--KGGTDRTGTM 348

  Fly   530 ICALLMYADLLREPEDAVQVFAVKR----HTINLR----PSEFRYLYYFGDI-------LRPTPL 579
            :||.|:.:::....::::..|..:|    |:...:    ||:.||:.||..:       |.|..:
Human   349 VCAFLIASEICSTAKESLYYFGERRTDKTHSEKFQGVKTPSQKRYVAYFAQVKHLYNWNLPPRRI 413

  Fly   580 LPHYKNTTLVSLSCQPVPRMTKARDGCRIYMEVYCNGNLLLSTLQDYEKMRLYQAGPGKIVLPI- 643
            | ..|:..:.|     :||.  .||   :.:::.....::.||:...:...|......||::.:
Human   414 L-FIKHFIIYS-----IPRY--VRD---LKIQIEMEKKVVFSTISLGKCSVLDNITTDKILIDVF 467

  Fly   644 -NLTACGDVTVVLFHARKGMVRPQGLKICQFQF--NTGFIPEPETLITFTNQDLDDL 697
             .|....||.|..|::.    .|.....|.|.|  :|.||  ....:.....:||:|
Human   468 DGLPLYDDVKVQFFYSN----LPTYYDNCSFYFWLHTSFI--ENNRLYLPKNELDNL 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	PKc_like	49..326	CDD:304357
		S_TKc	51..317	CDD:214567
		PTEN_C2	581..711	CDD:287393	26/121 (21%)
		DnaJ	<1110..1150	CDD:197617
TPTE	NP_954870.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..47
		PTP_VSP_TPTE	224..400	CDD:350360	43/180 (24%)
		PTEN_C2	409..539	CDD:402161	28/127 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2283
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810