Protein Alignment aux and gak

DIOPT Version :9

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: NP_001016350.2
• Gene: gak / 549104
• XenbaseID: XB-GENE-5893404
• Length: 1322
• Species: Xenopus tropicalis
• Alignment Length: 1366
• Identity: 457/1366 - (33%)
• Similarity: 665/1366 - (48%)
• Gaps: 293/1366 - (21%)

  Fly    27 PEALG--GRLDNDFVGQVVEVAGHRLRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGADMQAS 89
            |.:||  ||..:|||||.||:...::|:|.||||||:||||.||||.:|.:||||||:..:.:.:
 Frog    14 PGSLGGAGRDQHDFVGQTVEMGDMKMRVKRVIAEGGFAFVYEAQDVGSGKDYALKRLLSNEEEKN 78

  Fly    90 TAIINEINIHKQLSGHENIVAFV-GSSYTAPSTQLG-AQYLLLTELCKGGSLVDCFRTNNA---- 148
            .:||.||...|:||||.|||.|. .:|.....:..| .::|||||||: |.||:..  |.|
 Frog    79 KSIIQEICFMKKLSGHPNIVQFCSAASIGKEESDTGQGEFLLLTELCR-GQLVEFL--NKAECKG 140

  Fly   149 PFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEW 213
            |.:...||:||||..|||..:|.|.|||.|||:|:||.|:.|...:|||||||::|....|.:.|
 Frog   141 PLSCDTVLKIFYQTCRAVQHMHKQKPPIIHRDLKVENLLVSNQGTVKLCDFGSSTTIAHYPDYNW 205

  Fly   214 SANQRSMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYEDGGKLRI 278
            :|.||:.:||::...||||||:||::|.:||.|||.|.||||||||||.||:::||:|||.||||
 Frog   206 TAQQRATVEDEVTRNTTPMYRTPEIIDLYSNFPIGEKQDIWALGCILYLLCFKQHPFEDGAKLRI 270

  Fly   279 INANYMLPP-DPQYQCFSDIIRGCLKVNPFERLDITMVLEGLAALAETHNWSLKGPLDLHIMPIE 342
            :|..|.:|. |.:|..|..:|...:||||.|||.||.|:..|..:|...|.:.|.|:
 Frog   271 VNGKYSVPQNDTKYTVFHGLINSMIKVNPEERLSITEVVSQLQEIAAARNVNPKSPI-------- 327

  Fly   343 SLPAESPLKSSAYSEVYTEPLSAAIPSSYN--GH------------GSLLSSLRGGAGTLLKNIK 393
               .|...::..|.....:..|:..|.:..  .|            |.....|:||...:|.|||
 Frog   328 ---TELLEQNGGYGNTVIQRSSSGAPQNSKPLAHPGLTLTDDDQTSGGFFDILKGGTERILSNIK 389

  Fly   394 DTSTKVMQTMQQSLARNDLDISHITSRILVMPCPSDGFESTYKTNNIEDVRLSLESRFVPQKLSI 458
            |||:||:|:: .:.|:.|||:|:|||||.||..|::|.||..| ||||||||.|:|:. |...::
 Frog   390 DTSSKVIQSV-TNYAKGDLDLSYITSRIAVMSFPAEGVESAIK-NNIEDVRLFLDSKH-PGHYAV 451

  Fly   459 YNFGQRTEPRLPPPVRTVEAGSVYGCPQAHAPNLQGLFTVSADMYNFLNADPKSVVIVQTGDSGG 523
            ||...|..    .|.:.....|..|.....||||..|:::..:|:.:|..|||:|.||...| |.
 Frog   452 YNLCLRKY----RPSKFHNRVSECGWAGRRAPNLMNLYSICKNMHLWLKQDPKNVCIVHCTD-GR 511

  Fly   524 CTAATVICALLMYADLLREPEDAVQVFAVKRHTINLRPSEFRYLYYFGDILRPTPLLPHYKNTTL 588
            ..:|.|:|:.|.:..|....|.||.:|::||....:.||..||:.|..|::...|::||.|...:
 Frog   512 AASAVVLCSFLCFCRLFTTAEAAVYMFSMKRCPPGIWPSHKRYIEYMCDMMAEEPIIPHSKPILI 576

  Fly   589 VSLSCQPVPRMTKARDGCRIYMEVYCNGNLLLSTLQDYEKMRLYQAGPGKIVLPINLTACGDVTV 653
            .:::..|||..:|.|:|||.:.|||.....:.:|.|:|:|||.::...||..:|:|:|..|||.:
 Frog   577 RAITMTPVPLFSKQRNGCRPFCEVYVGDERVATTSQEYDKMRDFRNEDGKAEIPLNVTVQGDVLI 641

  Fly   654 VLFHARKGM-----VRPQGLKICQFQFNTGFIPEPETLITFTNQDLDDLPDPEQVTPRFCVSLSL 713
            |::|||..:     .:...:|:.|.||:|||:|...|.:.|...|||.....|:....|.|:|.:
 Frog   642 VIYHARSTLGGRLQAKMTSMKMFQIQFHTGFVPRNATTVKFAKYDLDACDIQEKYPDLFQVNLEV 706

  Fly   714 AVTDSESPPSHKPPWMPAKPKR-SPAALFSSDLEYAEMLDNFVTKPSTRSSPPPGARKSDRVSSP 777
            .|:..:...:..|||.....|| :|..||||..|..|||..| .||.....|...|:....::..
 Frog   707 EVSSRDKQATSSPPWENINTKRLNPKILFSSREEQQEMLSKF-GKPELPRQPGSTAQYEGDINME 770

  Fly   778 LVLPDVTET-------------------------------------------------------- 786
            ...||::::
 Frog   771 KPSPDLSDSETLQKNNFFQTLDWQDQSGVRNAQIGDQENVAKEDYENEYLSDSKSEASDEEFYSF 835

  Fly   787 ----------------------AHEL------PSPMPEPSPP----IDLLNLNQQ---------P 810
                                  |.|:      .:...|..||    :|||.||..         |
 Frog   836 PQGNRGIRCEENGPAVGTDDSVAREVLFEANKDTQSTEQGPPVEEEVDLLGLNPATNKVDTNTVP 900

  Fly   811 SDVP------------AADPLTSAKPSTDASF---DLLGAFGDDDSTGIGSAPIPDILPPPPLQQ 860
            |::.            .:|.|:....:....|   ||||..||....|          ||....:
 Frog   901 SEIKNSSSNIALLDNLFSDSLSGTADNVKTDFIGHDLLGNRGDFYFIG----------PPQTSVE 955

  Fly   861 PQ------PKINNDPFDIFG------------------SVDQGGVPSMKP---SGFPPF------ 892
            ..      |..::||||.|.                  |.:....|::.|   |..||.
 Frog   956 SSSNSFDIPFSSSDPFDPFAMSTSENKSSGPDLFEGLVSPNSASTPNVYPSVQSAAPPTSNIDFL 1020

  Fly   893 -VGSLPTFVAQ-PAATTNP----------------------------------SPTHPARASA-- 919
             :.:|||..:: .::.:||                                  |.:|.:.:|:
 Frog  1021 NLDNLPTRQSKIVSSASNPDLLGGWSSWEETSKSSNVFLPKLNKPAFEGPAYSSTSHLSTSSSSS 1085

  Fly   920 ---------DPFANIADLATGLNLNFNRSTLSGKSPVNTSPQPTQF-SSPTHKPSPSSQPQATFM 974
                     ||||::.:|:         |:|.|.|        ||| |..|.|.:.........:
 Frog  1086 FSQTKSSGFDPFADLDNLS---------SSLQGSS--------TQFPSQSTEKSAQKVSNSWQSV 1133

  Fly   975 HTPPTPQTLPSTSSIRTPTQPQAVPA-QSRPDYSRLHFD-----SQKAAQQPGTG---GSKNSDI 1030
            ..|..|||..:      |.|.||.|| ||:|:|: .:|.     .::..:.||.|   ....||
 Frog  1134 KQPAKPQTGGN------PWQSQAKPATQSKPNYT-ANFSVIGGREERGIRAPGFGLKPKVSESD- 1190

  Fly  1031 FADILGQQGYSFGSKMNQ-CPRSINEMRKEDLFKDMDPKKVRIMEWTDGKKNNIRALLCSMHTVL 1094
            |.|:|...|:|  :|.:: .|::|.|||:.:|.||.||.|::|::|.:||:.|||||:.::||||
 Frog  1191 FGDLLSNHGFS--AKTDRGGPKTIAEMRRHELTKDTDPLKLKILDWIEGKERNIRALISTLHTVL 1253

  Fly  1095 WD-NAKWQRCEMSTMVTPTEVKKAYRRACLAVHPDKHNGTENEEIAKLIFMELNNAWTDFENDAT 1158
            |: .::|:...|:.:|||.:|||.||:|.|.|||||..|...|:.||:||||||:||::|||..:
 Frog  1254 WEGESRWKPVNMAELVTPDQVKKYYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGS 1318

  Fly  1159 Q 1159
            :
 Frog  1319 R 1319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	PKc_like	49..326	CDD:304357	143/283 (51%)
		S_TKc	51..317	CDD:214567	141/272 (52%)
		PTEN_C2	581..711	CDD:287393	48/134 (36%)
		DnaJ	<1110..1150	CDD:197617	24/39 (62%)
gak	NP_001016350.2	STKc_GAK	38..319	CDD:270938	143/283 (51%)
		S_TKc	40..308	CDD:214567	140/270 (52%)
		PTEN_C2	569..707	CDD:287393	49/137 (36%)
		DnaJ	<1270..1315	CDD:99751	27/44 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	267	1.000	Domainoid score	I1844
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H3846
Inparanoid	1	1.050	529	1.000	Inparanoid score	I1200
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D296562at33208
OrthoFinder	1	1.000	-	-		FOG0001565
OrthoInspector	1	1.000	-	-		otm49351
Panther	1	1.100	-	-	LDO	PTHR23172
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2131
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.160