Protein Alignment aux and Stk16

DIOPT Version :10

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: NP_775165.1
• Gene: Stk16 / 286927
• RGDID: 629474
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 306
• Identity: 78/306 - (25%)
• Similarity: 139/306 - (45%)
• Gaps: 44/306 - (14%)

  Fly    47 GHRLRIKCV------------------IAEGGYAFVYVAQDVQTGTEYALKRLIGADMQASTAII 93
            ||.|   ||                  :.|||:::|.:.:.:..|..|||||::..:.|......
  Rat     2 GHAL---CVCSRGTVIIDNKRYLFVQKLGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDQEEAQ 63

  Fly    94 NEINIHKQLSGHENIVAFVGSSYTAPSTQLGAQY--LLLTELCKGGSL---VDCFRTNNAPFNPT 153
            .|.::|: |..|.||:..:..|.    .:.||::  .||....|.|:|   ::..:.........
  Rat    64 READMHR-LFQHPNILRLMAYSL----KERGAKHEAWLLLPFFKRGTLWNEIERLKDQGNFLTED 123

  Fly   154 CVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWSANQR 218
            .:|.:...:.|.:.::|::.  .||||:|..|.|:|::.|..|.|.||.:...:...   .:.|.
  Rat   124 QILPLLLGICRGLEAIHAKG--YAHRDLKPTNILLGDEGQPVLMDLGSMNQACIQVE---GSRQA 183

  Fly   219 SMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYE------DGGKLR 277
            ..|:|......|..||:||:....|:..|..:.|:|:|||:||.:.:.:.||:      |...|.
  Rat   184 LALQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALA 248

  Fly   278 IINANYMLPPDPQY-QCFSDIIRGCLKVNPFERLDITMVLEGLAAL 322
            :.| :..:|..|:: .....::...:.|:|.:|..|.::|..|.||
  Rat   249 VQN-DLSIPQSPRHSSALRQLLASMMTVDPQQRPHIPVLLSQLEAL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	Protein Kinases, catalytic domain	49..326	CDD:473864	76/304 (25%)
		PTP_auxilin-like	404..573	CDD:350361
		PTEN_C2	581..711	CDD:463081
		PHA03247	<698..1037	CDD:223021
		Herpes_BLLF1	<882..>999	CDD:282904
		DnaJ	<1110..1150	CDD:99751
Stk16	NP_775165.1	STKc_16	19..295	CDD:270888	73/286 (26%)
		Activation loop. /evidence=ECO:0000250	166..202		9/38 (24%)