Protein Alignment aux and D2045.7

DIOPT Version :10

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: NP_499311.2
• Gene: D2045.7 / 183953
• WormBaseID: WBGene00008424
• Length: 322
• Species: Caenorhabditis elegans
• Alignment Length: 298
• Identity: 78/298 - (26%)
• Similarity: 132/298 - (44%)
• Gaps: 58/298 - (19%)

  Fly    37 DFVGQVVEVAGHRLRIKCVIAEGGYAFVYVAQDVQTG---TEYALKRLIGADMQASTAIINEINI 98
            |.||:     |:.|:::..:|.||.|.:   .:|..|   ....:|:::....:....|:.||::
 Worm    17 DIVGE-----GYHLKVRKTVAVGGSAKI---MEVDPGGGKKPMIVKKMVAFSKREEERILLEIDL 73

  Fly    99 HKQLSGHE---NIVAFVGSSYTAPSTQLGAQYLL-----------LTELCKGGSLVDCFRTNNAP 149
            :|:|..:|   :::|.:....|        .|||           :.||..||. ||..:.
 Worm    74 YKKLENNEFVIDLMAHIVDDIT--------HYLLFDKYSQNFLEYIEELKIGGE-VDELKH---- 125

  Fly   150 FNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEWS 214
                  |:.|..:..|:..||...  .||.|||..|.|...| .||:.|||||:...:.  .:.|
 Worm   126 ------LKYFSGIVSAIEQLHGFE--FAHLDIKPANILKSGD-TIKMIDFGSATKMPIE--IKTS 179

  Fly   215 ANQRSMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHP----YEDGGK 275
            |:.....|| ...:.:.|||:||:.:....:.:...||:||||..||...|.::|    ||.||.
 Worm   180 ADHHRHKED-AEELCSMMYRAPELFNCEIGSTLTTAVDVWALGVCLYEFLYLENPFNKIYEQGGS 243

  Fly   276 LRIINANYMLPPDPQYQCFSD----IIRGCLKVNPFER 309
            :.:...:..:....:.:..|:    :|:..|.|:|.:|
 Worm   244 IALATQSPHMIKWNENRHISEKSINLIKSILIVDPNQR 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	Protein Kinases, catalytic domain	49..326	CDD:473864	74/286 (26%)
		PTP_auxilin-like	404..573	CDD:350361
		PTEN_C2	581..711	CDD:463081
		PHA03247	<698..1037	CDD:223021
		Herpes_BLLF1	<882..>999	CDD:282904
		DnaJ	<1110..1150	CDD:99751
D2045.7	NP_499311.2	Protein Kinases, catalytic domain	26..296	CDD:473864	73/284 (26%)