Protein Alignment aux and aak1b

DIOPT Version :9

• Sequence 1: NP_649438.1
• Gene: aux / 40527
• FlyBaseID: FBgn0037218
• Length: 1165
• Species: Drosophila melanogaster
• Sequence 2: XP_009303928.1
• Gene: aak1b / 100534954
• ZFINID: ZDB-GENE-091118-25
• Length: 1055
• Species: Danio rerio
• Alignment Length: 1167
• Identity: 248/1167 - (21%)
• Similarity: 392/1167 - (33%)
• Gaps: 414/1167 - (35%)

  Fly    20 GAAGNGAPEALGGRLDNDFVGQVVEVAGHRLRIKCVIAEGGYAFVYVAQDVQTGTEYALKRLIGA 84
            ||.|:|:....||    :|:|:...|..|::.::..:||||:|.|::.:..| |...||||:...
Zfish    21 GAGGSGSGSGAGG----NFIGRNFTVGRHQVTVEETLAEGGFAIVFLVRTNQ-GVRCALKRMYVN 80

  Fly    85 DMQASTAIINEINIHKQLSGHENIVAFVGSSYTAPSTQLGAQYLLLTELCKGGSLVDCFRTN-NA 148
            :.........||.|.:.|:||:|||.|:.||.||.......:..:|.:.|:||.:|:..... ..
Zfish    81 NEHDLQVCKREIQIMRDLNGHKNIVGFLDSSITAVGGGDVWEVFILMDFCRGGQVVNLMNQRLQT 145

  Fly   149 PFNPTCVLRIFYQMARAVASLHSQSPPIAHRDIKIENFLIGNDKQIKLCDFGSASTEVLSPTFEW 213
            .|:....|:||.....|||.||....||.|||:|:||.|:.:.....|||||||:.:..:|..|.
Zfish   146 GFSEQEALQIFCDTCEAVARLHQYKTPIIHRDLKVENILLHDRGHYVLCDFGSATMKFQNPQSEG 210

  Fly   214 SANQRSMLEDQLNTVTTPMYRSPEMLDTWSNNPIGPKVDIWALGCILYFLCYRKHPYEDGGKLRI 278
            .    :.:||::...||..||:|||::.::...|..|.||||:||:||.||:...|:.: .::.|
Zfish   211 V----TAVEDEIKKYTTLSYRAPEMVNLYNGKIITTKADIWAMGCLLYKLCFFTLPFGE-SQVAI 270

  Fly   279 INANYMLPPDPQY-QCFSDIIRGCLKVNPFERLDITMVLEGLAALAETHNWSLKGPLDLHIMPIE 342
            .:.|:.:|.:.:| |....:||..|:.:|.:|.||..|......||..         |..:..::
Zfish   271 CDGNFTIPDNSRYSQDMHRLIRYMLEPDPDKRPDIYQVSFFAFKLARR---------DCPVQNVK 326

  Fly   343 S--LPAESPLKSSAYSEVYTEPLSAAIPSSYNGHGSLLSSLRGGAGTLLKNIKDTSTKVMQTMQQ 405
            :  :||:.|           ||:.|:       ..:...|.......|...|..|.|.:....:.
Zfish   327 NSPIPAKLP-----------EPIRAS-------EAAAKKSQTQTKARLTDPIPTTETSITPRQRP 373

  Fly   406 SLARNDLDISHITSRIL-VMPC----------PSDGFESTYKTNNIEDVRLSLESRF-----VPQ 454
            ..|::.   |.....|| :.|.          |:...:....:.|:.....:|:|:.     .||
Zfish   374 KAAQSQ---SQALGGILPIQPAALTPRKRANLPAGAAQPIAVSVNLAQPAAALQSQKAQASPAPQ 435

  Fly   455 KLSIYNFGQRTEPRLPPPVRTVEAGSVYGCPQAHAPNLQGLFTVSADMYNFLNADPKSVVIVQTG 519
                    |:|:|                                             :.:..|.
Zfish   436 --------QKTQP---------------------------------------------IPVTVTA 447

  Fly   520 DSGGCTAATVICALLMYADLLREPEDAVQVFAVKRHTINLRPSEFRYLYYFGDILRPTPLLPHYK 584
            .:||..||:            ..|:.||..                          |.|
Zfish   448 TAGGIPAAS------------PTPQKAVAT--------------------------PPP------ 468

  Fly   585 NTTLVSLSCQPVPRMTKARDGCRIYMEVYCNGNLLLSTLQDYEKMRLYQAGPGKIVLPINLTACG 649
                    ..|.|....||...|....|                     |....:|.|...|
Zfish   469 --------SSPAPPTAPARSARRKQASV---------------------AQQQSVVAPPTAT--- 501

  Fly   650 DVTVVLFHARKGMVRPQGLKICQFQFNTGFIPEPETLITFTNQDLDDLPDPE-QVTPRFCVSLSL 713
                     :..:.:|...            .||........|     |.|: |::|.
Zfish   502 ---------QPAVAQPPAQ------------AEPTAAPPTVQQ-----PAPQSQISPE------- 533

  Fly   714 AVTDSESPP-----SHKPPWMPAKPKRSPAALFSSDLEYAEML----------------DNFVTK 757
               |:|..|     |..||..|...:::......||:.::.|.                :..:.|
Zfish   534 ---DAEERPAAPGLSQTPPSSPRTAQKAGHRRIQSDVTHSAMFGVPVSQSTQQLQAATAEASLNK 595

  Fly   758 PSTRSSPPPGARKSDRVS--------SPLVLPDVTETAHELPSPMPEPS-PPI-----------D 802
            ..:.|:.|..:.:|.:.|        :.:.:|....:|..|.||..:|: .|.           |
Zfish   596 SKSASATPSNSPQSSQQSVYQPAQQQASVSVPQAPASAANLTSPPTQPTWNPFDDDNFSKLTAED 660

  Fly   803 LLN-----LNQQP-------SD--VPAADPLTSAKPST-DASFDLLGAFGDDDSTGIGSAP---- 848
            |||     |..:|       ||  :|..:...||.||: :...|:||.   :...|:.:.|
Zfish   661 LLNKDFTKLADEPVEPLIVTSDSLIPGLEAAESAPPSSAERPADILGL---EPGAGLLAVPEKLI 722

  Fly   849 -----------IPDIL------------------------------PPPPLQQP----------- 861
                       :||:|                              ||....||
Zfish   723 EGLKSPDTSLMLPDLLSMADPFGSSIEETRDVNTDVCLDSLIPGLEPPQAQLQPVEAESASLVLT 787

  Fly   862 QPKINNDP-------------FDIFGSVDQG---GVPSMKP---SGFPPFVGSLPTFVAQPAATT 907
            .|.|.:|.             .|.|..:..|   .:|:.:|   |||.|          ..|.|.
Zfish   788 DPLIGDDSLLGGPLSSSSASCLDDFAVLSGGPSQNIPAAEPCLISGFEP----------SSAETA 842

  Fly   908 N-----PSPTHPARASADPFANIADLATGLNLNFNRSTLSGKSPVNTSPQPTQ------------ 955
            |     |.|...::.|.|...|:         |.|.|.    |.:.:|..|.:
Zfish   843 NEDEFDPIPVLVSKNSQDDLPNV---------NGNESA----SCIQSSDVPAEEEEEEEVLHMCS 894

  Fly   956 -----------FSSPTHKPSPSSQPQATFMHTPPTPQTLPSTSSIRTPTQ-PQAVPAQSRPD 1005
                       .::.:.|.||||.|..  ..:.|.|...|.:..|.|... ||..|:..:||
Zfish   895 GSKLLLLDSKLLNTTSLKLSPSSSPDV--FSSAPFPGCGPDSRDIFTSAPFPQIQPSHPQPD 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
aux	NP_649438.1	PKc_like	49..326	CDD:304357	95/278 (34%)
		S_TKc	51..317	CDD:214567	93/267 (35%)
		PTEN_C2	581..711	CDD:287393	18/130 (14%)
		DnaJ	<1110..1150	CDD:197617
aak1b	XP_009303928.1	STKc_NAK_like	43..316	CDD:270939	94/278 (34%)
		S_TKc	48..308	CDD:214567	92/265 (35%)
		BMP2K_C	810..1049	CDD:291930	39/170 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1989
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826336at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820