Protein Alignment beta-Man and C33G3.4

DIOPT Version :10

• Sequence 1: NP_649436.2
• Gene: beta-Man / 40524
• FlyBaseID: FBgn0037215
• Length: 908
• Species: Drosophila melanogaster
• Sequence 2: NP_510342.1
• Gene: C33G3.4 / 181517
• WormBaseID: WBGene00007904
• Length: 900
• Species: Caenorhabditis elegans
• Alignment Length: 958
• Identity: 292/958 - (30%)
• Similarity: 466/958 - (48%)
• Gaps: 184/958 - (19%)

  Fly    41 NWTITNQNGSLTIANQTLPLGIYS-AFAPQVLDS----YNDVGLRYLAYDNFTFSNFFQF----- 95
            ||..::.|.::. ...|:|..||| .:|..::|:    .|.:.|:::|.|::|:|..|:.
 Worm    31 NWEFSSSNKTVN-GTGTVPGDIYSDLYASGIIDNPLFGENHLNLKWIAEDDWTYSRKFRLIDLDD 94

  Fly    96 DVHHFNRGHINLTFHGIDTVSEIRLNHQLLGRTDNMFVRYSYEVSSLLQ-AENFLEVEIQSPVVA 159
            .|..|      |....:||::.:.:|.|.:..:.|.|:.|...|:.::. .||.:.::.:|.|..
 Worm    95 TVGAF------LEIESVDTIATVYVNGQKVLHSRNQFLPYHVNVTDIIALGENDITIKFKSSVKY 153

  Fly   160 ALARANALKEAKK----SVPPECPNERYHGECHMNMLRKMQASFSWDWGPAAPSAGIWKNVELEI 220
            |..||:   |.||    |:||:|..:.||||||.|.:||.|.||:|||||:.|:.||...:.:.|
 Worm   154 AEKRAD---EYKKIFGHSLPPDCNPDIYHGECHQNFIRKAQYSFAWDWGPSFPTVGIPSTITINI 215

  Fly   221 YEVAVIREVDVDVSRVNGSYW-NMHIRCFLDAGGWQ--------NFNGRLVLYAVELLDRPV-VV 275
            |               .|.|: :.:.:.....|.|:        ::..|.:.|:|::.:..: ..
 Worm   216 Y---------------RGQYFHDFNWKTRFAHGKWKVAFEFDTFHYGARTIEYSVQIPELGIKES 265

  Fly   276 DRYAI----------KNISHLAPVIEFDQAVPNGKVVTWWPNGYGEQKLYPLHFTLKTWLGPDGP 330
            |.|.:          |||..|:..:|.:..       .|||||.||||||.:..::       |.
 Worm   266 DYYRLSATKSLQTRSKNIMSLSIPMEHEPE-------RWWPNGMGEQKLYDVVVSM-------GG 316

  Fly   331 EVRSKTKSHKSLRVGFRTLDLVE---DPAPDGVGNTFLFRVNGVEMFMKGSNYIPSHLLPEMQTN 392
            :|:.|       ::||:|::||:   ||.....|..|.|::|...:|:||:|:||..:....:.|
 Worm   317 QVKEK-------KIGFKTVELVQDLIDPKKPEKGRNFYFKINDEPVFLKGTNWIPVSMFRSDREN 374

  Fly   393 -EQISHLLRSAKEAHMNMLRVWGGGVYESDYFYQLADSLGLLIWQDMMFACAMYPVNDEFLSSVR 456
             .:...||.|..|..||.:||||||.|||::||..|...|:|:|||:|||||:||..:||:.:..
 Worm   375 IAKTEFLLDSVAEVGMNAIRVWGGGFYESNHFYYYASKKGILVWQDLMFACALYPTTEEFIQNAE 439

  Fly   457 EEVRQNAMRLSHHPSVAIFVTNNENEAALVQNWY-GTLFERDRFESEYRELYLANVIHELKLVSH 520
            |||..|..|:|.|.||.:|..|||||||:..:|: .:.:...:...:|..||       .:|...
 Worm   440 EEVSYNVDRISQHTSVIVFSGNNENEAAIRGHWWKASNYTESQQVKDYVLLY-------QRLAKI 497

  Fly   521 SSRPQP----LVSSPSNGKASEPDNYISSNPQDNQNGDVHFYDYTKDGWDPGIFPRPRFVSEFGF 581
            :.:..|    ::||||||..:|.:..:|.||.|.:.||:|:|:...:.|....:..||..||:|.
 Worm   498 AKKVAPTIPFIMSSPSNGVETEEEGGVSKNPYDVRYGDIHYYNEFVNLWRDDTYLTPRCASEYGV 562

  Fly   582 QSFP---------GAYAWQ-RSKGEDDDLLGLITHRQHHPLGNVPVIALVERHLPLP-------- 628
            ||:|         ....|: .||.        :.||||||.|....:.::.:|||:|
 Worm   563 QSYPMKETMLNWINESDWEYTSKA--------MFHRQHHPGGIATNLLMIFQHLPIPAECGSKSV 619

  Fly   629 -------FPENENYATALIYFSQIAQAMATKVETELYRSLRDTP-----HRTMGALYWQLNDVWV 681
                   :..:.:|.:.|.||||:.|::|.|.:|..||..|:|.     ..||.|:||||||||.
 Worm   620 SDVPSCKYISSASYMSRLAYFSQVHQSIALKTQTLHYRRFRNTTTNEGLGNTMCAMYWQLNDVWA 684

  Fly   682 APSWSSIDFYGNWKLLHYWARDFLAPISIVALYEKSTDSLNISLICDQLEVDPREL-NVVANVHL 745
            ||:||:|||..|||:.||.||.|.:.:::.:..:::..:|.:.|:.|    :|..| |:..||
 Worm   685 APTWSTIDFEQNWKMAHYEARRFFSNVAVYSFADETDFNLKVFLLND----NPYLLHNITVNV-- 743

  Fly   746 WSQLLPRQSTSWDVTLRP---NGVQYDKVIA-ISDLLQGEFTRTNAFLELQLRRGQDVISRTHFF 806
                   |..||...|.|   |....|.|.| .|::|:...| .:...||.          .:.:
 Worm   744 -------QMLSWGNGLDPILTNEFHIDSVPAGSSEVLKTGIT-FSKITELS----------EYLY 790

  Fly   807 PSSIAGAVGI---ED---PGLEFEIASRTC--LNTTNVVR---NSVSISIQVKRPAVFVYLELLK 860
            .|::..:.|:   ||   |...||:...|.  :..::|.|   .:..::|...|.:.|.::...|
 Worm   791 VSTLYDSSGVKIHEDVLVPDFLFEVDFNTFGDVQISDVQRIDEKTYDLTITTDRVSPFTWITCKK 855

  Fly   861 PYRYTLSENGFMQTEPMHVVYLTFDAPLCARL---LRKSDLRVLTVND 905
            |:....|:|||      |::.......|.|:.   |.|||..|..:.:
 Worm   856 PFTGWFSDNGF------HMIQRLRKIRLIAKFEVDLEKSDFTVCNLKN 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
beta-Man	NP_649436.2	LacZ	95..>710	CDD:442481	226/683 (33%)
		Mannosidase_ig	719..808	CDD:465505	22/93 (24%)
C33G3.4	NP_510342.1	LacZ	30..>553	CDD:442481	181/574 (32%)
		Ig_mannosidase	822..897	CDD:465483	19/80 (24%)