Protein Alignment nAChRalpha4 and ort

DIOPT Version :9

• Sequence 1: NP_001097669.2
• Gene: nAChRalpha4 / 40521
• FlyBaseID: FBgn0266347
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_524406.1
• Gene: ort / 45910
• FlyBaseID: FBgn0003011
• Length: 485
• Species: Drosophila melanogaster
• Alignment Length: 340
• Identity: 66/340 - (19%)
• Similarity: 128/340 - (37%)
• Gaps: 70/340 - (20%)

  Fly    20 LSNYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLRWEPKEYGGVH 84
            :..|:|: ||.........|...:.:..|..::..:.....:::..|:|.|::||..........
  Fly    37 IKRYDKM-RPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQEYR 100

  Fly    85 MLHVP-SDHIWRPDIVLYNNADGNFEVTLATKAT------IYSEGLVEWKPPAIYKSSCEIDVEY 142
            :|.|. ..::|||| ..:.||.   .||..|...      :|.:..:.:......|.||.::...
  Fly   101 LLEVDWLKNMWRPD-SFFKNAK---SVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNFAI 161

  Fly   143 FPFDEQTCVLKFGSWTYDGFKVDLRHMDEQQGSNVVAVGVDLSEFYMSVEWD------------I 195
            :|.|.|.|.|:..|         |.|..:.                :..:||            :
  Fly   162 YPHDTQECKLQMES---------LSHTTDD----------------LIFQWDPTTPLVVDENIEL 201

  Fly   196 LEVPAVRNEKF----------YTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFY 250
            .:|..:|||..          :||     |::.|  |::|:.::|..|..||...|..::.::|:
  Fly   202 PQVALIRNETADCTQVYSTGNFTC-----LEVVF--TLKRRLVYYVFNTYIPTCMIVIMSWVSFW 259

  Fly   251 L-PSDSGEKVTLSISILISLHVFFLLVVEIIPPTS---LVVPLLGKYLIFAMILVSISICVTVVV 311
            : |..:..:|||.::.|::|..........:||.|   .|...:....:|..:.:.....:.:|:
  Fly   260 IKPEAAPARVTLGVTSLLTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVL 324

  Fly   312 LNVHFRSPQTHKMAP 326
            .:.....|..:...|
  Fly   325 SDTPIPKPMAYPPKP 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha4	NP_001097669.2	LIC	1..505	CDD:273305	66/340 (19%)
		Neur_chan_LBD	12..227	CDD:280998	46/235 (20%)
		Neur_chan_memb	234..505	CDD:280999	18/97 (19%)
ort	NP_524406.1	LIC	31..481	CDD:273305	66/340 (19%)
		Neur_chan_LBD	38..235	CDD:280998	45/233 (19%)
		Neur_chan_memb	243..>334	CDD:280999	17/90 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100