Protein Alignment nAChRalpha4 and Rdl

DIOPT Version :9

• Sequence 1: NP_001097669.2
• Gene: nAChRalpha4 / 40521
• FlyBaseID: FBgn0266347
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001261617.1
• Gene: Rdl / 39054
• FlyBaseID: FBgn0004244
• Length: 608
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 74/325 - (22%)
• Similarity: 131/325 - (40%)
• Gaps: 43/325 - (13%)

  Fly     4 GAVAGNPDAKRLYDDLLSNYNKLVRPVVN--TTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQ 66
            |::.|:.:...:.|....:|:|.|||...  ..:|......|.:|.|.:|.:.   .|.:.:..|
  Fly    51 GSMLGDVNISAILDSFSVSYDKRVRPNYGGPPVEVGVTMYVLSISSLSEVKMD---FTLDFYFRQ 112

  Fly    67 SWYDYKLRWEPKEYGGVHMLHVPSD---HIWRPDIVLYNNADGNFEVTLATK--ATIYSEGLVEW 126
            .|.|.:|.:..:.  ||..|.|.|:   :||.||....|.....|.:...:.  ..::..|.:..
  Fly   113 FWTDPRLAYRKRP--GVETLSVGSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITR 175

  Fly   127 KPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFKVDLRHMDEQQGSNVVAVGVDLSEFYMSV 191
            .......:||.::::|||.|.|.|.::..|:.|.  ..|:|:....          .||...||.
  Fly   176 SIRLTITASCPMNLQYFPMDRQLCHIEIESFGYT--MRDIRYFWRD----------GLSSVGMSS 228

  Fly   192 EWDILEVPAVR--------NEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLT 248
            |   :|:|..|        .|...|..:  |..:...|...|...:|.:.|.||...|..::.::
  Fly   229 E---VELPQFRVLGHRQRATEINLTTGN--YSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVS 288

  Fly   249 FYLPSD-SGEKVTLSISILISLHVFFLLVVEIIPPTSLVVPL---LGKYLIFAMILVSISICVTV 309
            |:|..: :..:|.|.::.::::..........:|..|.|..:   ||  ..|.|:..|:....||
  Fly   289 FWLNRNATPARVALGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLG--TCFVMVFASLLEYATV 351

  Fly   310  309
              Fly   352  351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha4	NP_001097669.2	LIC	1..505	CDD:273305	74/325 (23%)
		Neur_chan_LBD	12..227	CDD:280998	53/229 (23%)
		Neur_chan_memb	234..505	CDD:280999	18/80 (23%)
Rdl	NP_001261617.1	LGIC_ECD_GABAR_RDL-like	83..266	CDD:349809	46/204 (23%)
		Neur_chan_memb	274..588	CDD:397193	18/80 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447339
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030