Protein Alignment nAChRalpha4 and CG12344

DIOPT Version :9

• Sequence 1: NP_001097669.2
• Gene: nAChRalpha4 / 40521
• FlyBaseID: FBgn0266347
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001286298.1
• Gene: CG12344 / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 314
• Identity: 65/314 - (20%)
• Similarity: 129/314 - (41%)
• Gaps: 38/314 - (12%)

  Fly    22 NYNKLVRPVVNTTDVLKVCIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLR------WEPKEY 80
            ||.|.:||.......:.|...:.:..:..:|:::.....::::.|.|.:.:|.      .|..:|
  Fly    43 NYVKEIRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107

  Fly    81 GGVHMLHVPSDHIWRPDIVLYNNADGNFEVTLA---TKATIYSEGLVEWKPPAIYKSSCEIDVEY 142
              |.:|....::.|:||....|:..... .||.   |..|:|....|.:........:|:::.:.
  Fly   108 --VTLLPEVFENFWQPDPYFLNSKIAEI-ATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEFQL 169

  Fly   143 FPFDEQTCVLKFGSWTYDGFKVDLRHMDEQQGSNVVAVGVDLS------EFYMSVEWDILEVPAV 201
            :|.|.|.|.:...|::.:..||.||..|.         ||.|:      ::.:....::.|....
  Fly   170 YPMDIQVCPIYIESFSSNNQKVKLRWSDS---------GVTLNPELKLLQYNLGQPLELEESDGY 225

  Fly   202 RNEKFYTCCDEPYLDITFNITMRRKTLFYTVNIIIPCMGISFLTVLTFYLPSDS-GEKVTLSISI 265
            ..||...     :..:|......|:...:.:....|...:..|:..:|:|..|: ..:|||.::.
  Fly   226 MPEKVGN-----FSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTC 285

  Fly   266 LISLHVFFLLVVEIIPPTSLVVPLLGKYLIFAMILVSISIC--VTVVVLNVHFR 317
            :::|...|  ....|||.: .|..|..::...|:.|..::.  |.|.||:|.::
  Fly   286 MLTLVTMF--TGADIPPVA-YVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha4	NP_001097669.2	LIC	1..505	CDD:273305	65/314 (21%)
		Neur_chan_LBD	12..227	CDD:280998	43/219 (20%)
		Neur_chan_memb	234..505	CDD:280999	22/87 (25%)
CG12344	NP_001286298.1	LIC	8..441	CDD:273305	65/314 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100