Protein Alignment alpha-Cat and Vinc

DIOPT Version :9

• Sequence 1: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001284813.1
• Gene: Vinc / 31201
• FlyBaseID: FBgn0004397
• Length: 961
• Species: Drosophila melanogaster
• Alignment Length: 991
• Identity: 217/991 - (21%)
• Similarity: 387/991 - (39%)
• Gaps: 184/991 - (18%)

  Fly    29 TMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKS-KRASALVAAVEKATENFIQKGEQIAYENPD-- 90
            |.::|..|:|:..||:.||...  .:.:.|.: ...|..|..|..|..|.::.|......:.|
  Fly     6 TKTIESILDPVAQQVSRLVILH--EEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKI 68

  Fly    91 ITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNLLSAVTRLLILADMVDVHLL 155
            :.|:|.:|:..|:.....:..|:.....||.|...|..::..:|.:|...:.||:..|..:|..:
  Fly    69 LRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKI 133

  Fly   156 LKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDDLAAARAMLK 220
            ::....|.|.|...:..::.::|:..::.......::.::...|::||......:.|......:|
  Fly   134 IQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVK 198

  Fly   221 KHSTMLLTASKVYVRHPE-----LDLAKVNRDF-------------------------------- 248
            ..:.:|:.:.|||:...|     .:.|..||::
  Fly   199 TLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLT 263

  Fly   249 ILKQVCDAVNTISDVAQGKSSQPTDIYSGAGELAAALDDFDEGIVMDPMTYSEKRS--------R 305
            :||::.:|::...:.|....|.|..:..|.||.|...       |:|..|...:|.        |
  Fly   264 VLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQ-------VIDNATEISERCLPQDSYPIR 321

  Fly   306 QLLEE----------------------------------RLESIISAAALMADA----------- 325
            :|.:|                                  .|:|::..|.|..|.
  Fly   322 KLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQ 386

  Fly   326 ----------------DCTRDERRERIVAE--------CNAVRQA-LQDLLSEYMSNMSQKDNS- 364
                            |....||...::.|        |...::| :|.|..|......|...|
  Fly   387 GRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSG 451

  Fly   365 PGLSRAIDQMCRKTRDLRRQLRKAVVDHVSDSFLETTTPLLDLIEA-----AKSGNEKKVREKSE 424
            |...:|..|:.:|..:|:..::.|:|:.:...|::.:|||....||     ...|.|:...:||.
  Fly   452 PAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSN 516

  Fly   425 IFTKHAEKLVEVANLVCS--MSNNEDGVKMVRYAAAQIESLCPQVINAASILTVRPNSKVAQENM 487
            .....:::..:.:.:|.:  ...|:...:::..:|||::||.||:|:|..|....|.||.|.|::
  Fly   517 NLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHL 581

  Fly   488 TTYRQAWEVQVRILTEAVDDITTIDDFLAVSENHILEDVNKCVMALQVGDARDLRATAGAIQGRS 552
            ...:|.:...|..:....|..|...||:..||.|:......|..|:.....:.:......|....
  Fly   582 QNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLI 646

  Fly   553 SRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQVMMKFDQRVGAAVGALSNNSNKDVD------- 610
            :||..|.:.|.||.|..::|:|:..|..        :.::.:.|.||.....:....|
  Fly   647 NRVLLVAKQEADNSEDPVFTERLNAAAN--------RLERSLPAMVGDAKLVATNIADPAAAAAW 703

  Fly   611 ENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVEDLTLETRSRSSAHTGDQTVDEYP- 674
            :|.|   .||:.| |||:|.|:...: ...|.|... .|:.:|       |:.|..:|..:..|
  Fly   704 KNSF---QRLLGD-VREVRDAIAPPQ-PPPLPTSLP-PPIPEL-------SALHLSNQNAERAPP 755

  Fly   675 ----DISGICTAREAMRKMTEEDK-----QKIAQQVELFRREKLTFDSEVAKWDDTGNDIIFLAK 730
                ...|:...|....:..:||:     ...|.|..|.....|  ..||.:|....|:||..||
  Fly   756 RPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGL--HQEVRQWSSKDNEIIAAAK 818

  Fly   731 HMCMIMMEMTD--FTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCPESSTKKDLLAYL 793
            .|.::|..:::  .:..||   :..::|..||||:||...:.:|.:|:|.||.:...:.:||...
  Fly   819 RMAILMARLSELVLSDSRG---SKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVC 880

  Fly   794 QRIALYCHQIQITSKVKADVQNISGELIVSGLDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTR 858
            :||.....|::|.|.|||.:....|.  ....::...|:..|:|||.:|..||:.:..||.|...
  Fly   881 ERIPTIGTQLKILSTVKATMLGAQGS--DEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRS 943

  Fly   859 QGTVSSPIVVWKMKAP 874
            ..|  |..:.|..:.|
  Fly   944 DQT--SNRLQWVRRQP 957

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Cat	NP_524219.1	Vinculin	87..877	CDD:395830	202/932 (22%)
Vinc	NP_001284813.1	Vinculin	63..960	CDD:279395	202/932 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3681
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740