Protein Alignment alpha-Cat and ctnna1

DIOPT Version :10

• Sequence 1: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_571531.1
• Gene: ctnna1 / 30741
• ZFINID: ZDB-GENE-991207-24
• Length: 907
• Species: Danio rerio
• Alignment Length: 912
• Identity: 556/912 - (60%)
• Similarity: 717/912 - (78%)
• Gaps: 18/912 - (1%)

  Fly     9 TLTDFGQIALKWDPKNLEIRTMSVEKTLEPLVLQVTTLVNT--KGPSKKKKGKSKRASALVAAVE 71
            |..:...|..|||||:|||||::||:.|||||.|||||||:  ||||.||||:||:|..|.|:|:
Zfish     2 TSINTANINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNSSNKGPSNKKKGRSKKAHVLAASVD 66

  Fly    72 KATENFIQKGEQIAYENPDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAARNL 136
            :||:||::|||:||.|:..:.:|:..||::|:|.|::|.:|:.||:||||||:||||||||||.|
Zfish    67 EATQNFLEKGEKIAKESQFLKEELTAAVEDVRKQGESMKMASGEFAEDPCSSVKRGNMVRAARAL 131

  Fly   137 LSAVTRLLILADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQ 201
            |||||.||:||||.||:.||..|.:||::|.|::||.::.:|....:.......:|...||||||
Zfish   132 LSAVTHLLVLADMADVYQLLLQLKLVEENLMKVRNAGTEQDLGIQYKALKPEVDKLNMMAAKRQQ 196

  Fly   202 ELKDPQLRDDLAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVAQG 266
            ||||...:|.:||||.:|:::..||.|||:..::||::...|.|||.|.||:..||:.||:.||.
Zfish   197 ELKDVHHKDQMAAARGVLQRNVPMLYTASRACLQHPDVAAYKANRDLIYKQLQHAVSGISNAAQA 261

  Fly   267 KSSQPTDI--YSGAGELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADADCTR 329
            .||:.:..  .:|.||||.||::||:.|::||:::||:|.|..||||||||||.||||||:.|||
Zfish   262 TSSEDSSFSQTAGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTR 326

  Fly   330 DERRERIVAECNAVRQALQDLLSEYMSNMSQKDNSPGLSRAIDQMCRKTRDLRRQLRKAVVDHVS 394
            |:||||||||||:|||||||||||||.|..:|:.|..|:.|||:|.:|||||||||||||:||||
Zfish   327 DDRRERIVAECNSVRQALQDLLSEYMGNAGRKEKSDALNTAIDRMTKKTRDLRRQLRKAVMDHVS 391

  Fly   395 DSFLETTTPLLDLIEAAKSGNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDGVKMVRYAAAQ 459
            ||||||..|||.||||||:||||:|:|.:::|.:||.||:|||||.||:||||:|||:||.||:|
Zfish   392 DSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHANKLIEVANLACSISNNEEGVKLVRMAASQ 456

  Fly   460 IESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDFLAVSENHILE 524
            :|:|||||||||..|..:|||||||:||..::..||.|||:||:||||||:|||||.||||||||
Zfish   457 LETLCPQVINAALALAAKPNSKVAQDNMDLFKDQWEKQVRVLTDAVDDITSIDDFLCVSENHILE 521

  Fly   525 DVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQVMMK 589
            ||||||:|||..|...|..|||||:||::||.:||.:|||||.|.:||::||||.|:|.:.||.:
Zfish   522 DVNKCVIALQEKDVDGLDRTAGAIRGRAARVVHVVTSEMDNYMPGVYTEKVLEATKLLTETVMPR 586

  Fly   590 FDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVEDLT 654
            |.::|.|||.|||.|:.:.||||:|||||||||||||:||:||||.|:.|:|| |::|| .||
Zfish   587 FTEQVEAAVEALSANNGQPVDENEFIDASRLVYDGVRDIRKAVLMIRTPEELD-DSDFE-TED-- 647

  Fly   655 LETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQQVELFRREKLTFDSEVAKWD 719
            .::|||:|..|.|..:     |:| .:||..|.::.:|.|.|||:||..|:.||...|:||:|||
Zfish   648 FDSRSRTSVQTEDDQL-----IAG-QSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWD 706

  Fly   720 DTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCPESS 784
            |:|||||.|||.||||||||||||||:||||.|.|||:|||||:|||:::|||.|.||:|||:|:
Zfish   707 DSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRAIADQCPDSA 771

  Fly   785 TKKDLLAYLQRIALYCHQIQITSKVKADVQNISGELIVSGLDSATSLIQAAKNLMNAVVLTVKYS 849
            .|:|||||||||||:|||:.|.|||||:|||:.|||:|||||||.|||||||||||:||.|||.|
Zfish   772 CKQDLLAYLQRIALFCHQLNICSKVKAEVQNLGGELVVSGLDSAMSLIQAAKNLMNSVVSTVKAS 836

  Fly   850 YVASTKYTRQGTVSS---PIVVWKMKAPEKKPLVRPEKPEEVRA-KVRKGSQKKVQNPIHALSEF 910
            |||||||.:...:.|   |.:.||||||||||||:.||.::.:. ||::.||||..||:.|||||
Zfish   837 YVASTKYQKSQDMQSLNMPAISWKMKAPEKKPLVKREKLDDGQTNKVKRSSQKKHINPVQALSEF 901

  Fly   911 QS 912
            ::
Zfish   902 KA 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Cat	NP_524219.1	Vinculin	26..877	CDD:460040	528/857 (62%)
ctnna1	NP_571531.1	Vinculin	19..867	CDD:460040	528/857 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	870..895		10/24 (42%)