Protein Alignment alpha-Cat and Ctnnal1

DIOPT Version :9

• Sequence 1: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001100119.1
• Gene: Ctnnal1 / 298019
• RGDID: 1311434
• Length: 731
• Species: Rattus norvegicus
• Alignment Length: 870
• Identity: 207/870 - (23%)
• Similarity: 351/870 - (40%)
• Gaps: 207/870 - (23%)

  Fly    25 LEIRTMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKSKRASALVAAVEKATENFIQKGEQIAYENP 89
            |||||.|||:||.|||.|:|||:|.|..:||.....:....:..||..|...|::.||.||.||.
  Rat    29 LEIRTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENW 93

  Fly    90 DITQEMLTAVDEVKKTGDAMSIAA-----REFSEDPCSSL---KRGNMVRAARNLLSAVTRLLIL 146
            |:.:|:..|..|.|:.|:.::...     .....|...::   |.| :|:|||.|||:||::|:|
  Rat    94 DLKEEISIACIEAKQAGETIASLTDVTKWNHLESDGQVTILTDKTG-VVQAARLLLSSVTKVLLL 157

  Fly   147 ADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDD 211
            ||.|.:..::.|.:.|...:.:|:..:|..|.:....|||....|.......||.:|||.:.:..
  Rat   158 ADQVVIKQIVTSRNKVLATMERLERVNSFQEFVQIFSQFGNEMVEFAYLTGDRQNDLKDEKKKAR 222

  Fly   212 LAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVA------QGKSSQ 270
            :|.|||:|:|.:.|||||||..:|||..:.|..|::.:..::..|:..:.::.      :...|.
  Rat   223 MAVARAVLEKGTMMLLTASKTCLRHPSCESAHKNKEGVFDRMRAALEKVIEIVTDCRLNRDTDSS 287

  Fly   271 PTDIYSGAGELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADADCTRDERRER 335
            ...|::|..||...::...|.:..:        |::.|...||.|:.......|:..|..|.|||
  Rat   288 SVSIFTGIKELKLNMEALRENVYFE--------SKENLSAALEVILERVEDFTDSAYTSHEHRER 344

  Fly   336 IVAECNAVRQALQDLLSEYMSNMSQKDNSPG---------LSRAIDQMCRK----TRDLRRQLRK 387
            |:......|..:|..:|.:|...|:|..|..         :|.::|::.::    ...|...|.|
  Rat   345 ILELSAQARTEVQQFISVWMQAQSRKTKSAAEELELTVLKVSHSLDELRKELHCTAMQLAADLLK 409

  Fly   388 AVVDHVSDSFLETTTPLLDLIEAAKSGNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDGVKM 452
            ...|||....|:.|         ...||.:.:.|.:...::..|:|||...|:..:|..|.....
  Rat   410 FHADHVVLKALKVT---------GVEGNLEALAEYACKLSEQKEQLVETCRLLRHVSGTEPLEIT 465

  Fly   453 VRYAAAQIESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDFLAV 517
            ..:|....:....|:|:||..||:.|:||:|:||:..:.:|||.|       :.|:.|:
  Rat   466 CMHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQ-------ISDLATL------ 517

  Fly   518 SENHILEDVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAVKVL 582
                                   ||..:...:||..          :.|:.....|
  Rat   518 -----------------------LREISDVFEGRRG----------EKYDHLSLPK--------- 540

  Fly   583 RDQVMMKFDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEF 647
                             .:.||:|....::|
  Rat   541 -----------------PMKNNANLKSVKSD---------------------------------- 554

  Fly   648 EPVEDLTLETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQ---QVELFRREKL 709
                                                    |...|::.|||:   ::.|...:.
  Rat   555 ----------------------------------------KPDSEEQAKIAKLGLKLGLLSSDA- 578

  Fly   710 TFDSEVAKWDDTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDKLTR 774
              |.|:.||:|..|:|:...::|..:...:..||||.|||||:.|:|:..:..:..|.||....:
  Rat   579 --DCEIEKWEDDDNEIVRHGRNMSRMAYSLYLFTRGEGPLKTSQDLIHFLEVFATEGLKLTSSIQ 641

  Fly   775 EIAEQCPESSTKKDLLAYLQRIALYCHQIQITSKVKADVQNISGELIVSGLDSATSLIQAAKNLM 839
            ..::|..:.. |..||..:.::...|||:|..:|.     ::..::.:. :|...:.|   :::|
  Rat   642 SFSKQLKDDD-KLMLLLEINKLIPLCHQLQTITKT-----SLQSKVFLK-VDKCVTKI---RSMM 696

  Fly   840 NAVVLTVKYSYVASTKYTRQGTVSS 864
            ..||..:...|....|......||:
  Rat   697 TLVVQLLSLCYKLLKKMGNDRWVSA 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Cat	NP_524219.1	Vinculin	87..877	CDD:395830	178/808 (22%)
Ctnnal1	NP_001100119.1	Vinculin	91..674	CDD:279395	168/750 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3681
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810