Protein Alignment alpha-Cat and Ctnna2

DIOPT Version :9

• Sequence 1: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_017448033.1
• Gene: Ctnna2 / 297357
• RGDID: 1305060
• Length: 966
• Species: Rattus norvegicus
• Alignment Length: 962
• Identity: 584/962 - (60%)
• Similarity: 735/962 - (76%)
• Gaps: 68/962 - (7%)

  Fly     8 GTLTD-FGQIALKWDPKNLEIRTMSVEKTLEPLVLQVTTLVNT--KGPSKKKKGKSKRASALVAA 69
            |::|. ...|.||||||:|||||::||:.|||||.||||||||  ||||.||||:||:|..|.|:
  Rat    12 GSMTSATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAAS 76

  Fly    70 VEKATENFIQKGEQIAYENPDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSSLKRGNMVRAAR 134
            ||:||:||::||||||.|:.|:.:|::.||::|:|.|:.|.||:.||::|||||:|||.||||||
  Rat    77 VEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAAR 141

  Fly   135 NLLSAVTRLLILADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKR 199
            .||||||||||||||.||..||..|.|||:.|..:|||:::.:|.:..::||:...:|...||:|
  Rat   142 ALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARR 206

  Fly   200 QQELKDPQLRDDLAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFILKQVCDAVNTISDVA 264
            |||||||..||::||||..|||::|||.|||:.::|||::...:.|||::.|||.:|:..||..|
  Rat   207 QQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISSAA 271

  Fly   265 QGKSSQPTDI---YSGAGELAAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADAD 326
            |..|  |||.   ::|.|||||||::||..|::||||:||.|.|..||||||||||.||||||:.
  Rat   272 QATS--PTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSS 334

  Fly   327 CTRDERRERIVAECNAVRQALQDLLSEYMSNMSQKDNSPGLSRAIDQMCRKTRDLRRQLRKAVVD 391
            ||||:||||||||||||||||||||||||:|..:|:....|:.|||:|.:|||||||||||||:|
  Rat   335 CTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMD 399

  Fly   392 HVSDSFLETTTPLLDLIEAAKSGNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDGVKMVRYA 456
            |:|||||||..|||.|||||||||||:|:|.:::|.:||.||||||||.||:||||:|||:||.|
  Rat   400 HISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMA 464

  Fly   457 AAQIESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDFLAVSENH 521
            |.||:||||||||||..|..||.|||||:||..::..||.|||:|||||||||::||||:|||||
  Rat   465 ATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENH 529

  Fly   522 ILEDVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAVKVLRDQV 586
            |||||||||:|||.||...|..|||||:||::||.:::.|||:|||..:||::||||.|:|.:.|
  Rat   530 ILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETV 594

  Fly   587 MMKFDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTDTEFEPVE 651
            |.:|.::|..|:.|||.|..:..:||:|||||||||||||:||:||||.|:.|:|:.|::||. |
  Rat   595 MPRFAEQVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQ-E 658

  Fly   652 DLTLETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQQVELFRREKLTFDSEVA 716
            |  .:.|||:|..|.|..:     |:| .:||..|.::.:|:|.|||:|||:|.:||...|:|||
  Rat   659 D--YDVRSRTSVQTEDDQL-----IAG-QSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVA 715

  Fly   717 KWDDTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDKLTREIAEQCP 781
            ||||:|||||.|||.||||||||||||||:||||.|.|||||||||:|||:::|||.|.:|:|||
  Rat   716 KWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCP 780

  Fly   782 ESSTKKDLLAYLQRIALYCHQIQITSKVKADVQNISGELIVSG---------------------- 824
            :|:.|:|||||||||||||||:.|.|||||:|||:.|||||||
  Rat   781 DSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGTGVQSTFTTFYEVDCDVIDGGR 845

  Fly   825 --------------------------LDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTR-QGT- 861
                                      |||||||||||||||||||||||.||||||||.: .||
  Rat   846 ASQLSTHLPTCAEGAPIGSGSSDSSMLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKVYGTA 910

  Fly   862 -VSSPIVVWKMKAPEKKPLVRPEKPEEVRAKVRKGSQKKVQNPIHALSEFQS 912
             |:||:|.||||||||||||:.|||||.:.:||:|||||..:|:.|||||::
  Rat   911 AVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFKA 962

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Cat	NP_524219.1	Vinculin	87..877	CDD:395830	507/843 (60%)
Ctnna2	XP_017448033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	672	1.000	Domainoid score	I138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H68394
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56187
OrthoDB	1	1.010	-	-		D405587at33208
OrthoFinder	1	1.000	-	-		FOG0002407
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103558
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1596
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830