Protein Alignment alpha-Cat and ctnnal1

DIOPT Version :9

• Sequence 1: NP_524219.1
• Gene: alpha-Cat / 40517
• FlyBaseID: FBgn0010215
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001137526.1
• Gene: ctnnal1 / 100034581
• ZFINID: ZDB-GENE-060503-507
• Length: 754
• Species: Danio rerio
• Alignment Length: 889
• Identity: 229/889 - (25%)
• Similarity: 380/889 - (42%)
• Gaps: 227/889 - (25%)

  Fly    25 LEIRTMSVEKTLEPLVLQVTTLVNTKGPSKKKKGKSKRASALVA-AVEKATENFIQKGEQIAYEN 88
            |||:|.|||:||.|||.|:|||:|.|...||.: |:.||...|. ||..|...|:..||.||.||
Zfish    15 LEIQTRSVEQTLIPLVSQITTLINHKDKLKKTE-KTLRAIQRVGQAVSVAVGRFVAVGEAIAAEN 78

  Fly    89 PDITQEMLTAVDEVKKTGDAMSIAAREFSEDPCSS-------LKRGNMVRAARNLLSAVTRLLIL 146
            .|:.:||..|..|.::.|..::......|.:.|..       ..|..||:|||.|||:||::|:|
Zfish    79 EDLKEEMGLACFEARRAGTGIAQLTDVSSLEHCDGDGRSTVFSDRTGMVKAARMLLSSVTKVLVL 143

  Fly   147 ADMVDVHLLLKSLHIVEDDLNKLKNASSQDELMDNMRQFGRNAGELIKQAAKRQQELKDPQLRDD 211
            ||.:.:..::.|.:.|...|.:|:..|:..|.:....|||....|.......||.:|||.:.|..
Zfish   144 ADCIVIKQIISSRNKVLVTLEQLERVSTFQEFVQIFSQFGNEMVEFAHLTGDRQNDLKDEKKRAR 208

  Fly   212 LAAARAMLKKHSTMLLTASKVYVRHPELDLAKVNRDFI-------LKQVCDAVNTISDVAQGKSS 269
            :|||||:|:|.:.|||||||..:|||:.:.|::|::.:       |:||.:.|.......:.| :
Zfish   209 MAAARAVLEKCTMMLLTASKTCLRHPDCESARINKEAVFQRMRIALEQVIEIVTDTRSSGEAK-A 272

  Fly   270 QPTDIYSGAGEL---AAALDDFDEGIVMDPMTYSEKRSRQLLEERLESIISAAALMADADCTRDE 331
            .|..||:|..:.   ..||.|...|:           |.:.:..:||:::.......|:..||.|
Zfish   273 LPVSIYAGIKDFKVKVEALRDSLYGV-----------SCEAVAAQLEALVEKTEDFTDSAYTRHE 326

  Fly   332 RRERIVAECNAVRQALQDLLS--EYMSNMSQKDNSPGLSRAIDQMCRKTRDLRRQLRKAVVDHVS 394
            :||.|:..|...||..:.|::  .:..::..|:.:..:..:|.:.|:...|||::|.|..|..
Zfish   327 QRETIIQLCQITRQETKQLINTWRHAQSLKAKEATDEMELSILKTCQCVSDLRQELHKVAVGR-- 389

  Fly   395 DSFLETTTPLLDL------IEAAKS----GNEKKVREKSEIFTKHAEKLVEVANLVCSMSNNEDG 449
                  .|.||.|      ::|.|:    ||.:.|.:.:...|:|.|:|||...|:|.:|..|..
Zfish   390 ------ATELLKLHSDHLVLQALKASGGDGNLEAVADYASTLTEHNEQLVETCRLLCHVSGTEPL 448

  Fly   450 VKMVRYAAAQIESLCPQVINAASILTVRPNSKVAQENMTTYRQAWEVQVRILTEAVDDITTIDDF 514
            .....:|......:.||:|:||..|.:.|.||:|:||:..:.:|||.|:
Zfish   449 EITCIHAEETFRVIGPQIISAAQTLALHPTSKIAKENLDVFCEAWESQL---------------- 497

  Fly   515 LAVSENHILEDVNKCVMALQVGDARDLRATAGAIQGRSSRVCNVVEAEMDNYEPCIYTKRVLEAV 579
                          |.||:.:.:..|
Zfish   498 --------------CDMAILLKEIND--------------------------------------- 509

  Fly   580 KVLRDQVMMKFDQRVGAAVGALSNNSNKDVDENDFIDASRLVYDGVREIRRAVLMNRSSEDLDTD 644
                                                     |::|.|..::..|
Zfish   510 -----------------------------------------VFEGRRGDKKTYL----------- 522

  Fly   645 TEFEPVEDLTLETRSRSSAHTGDQTVDEYPDISGICTAREAMRKMTEEDKQKIAQ-QVELFRREK 708
                        :..|...|:           :.:.|.:.|  |:..|::..||: .:||.   .
Zfish   523 ------------SLPRPGKHS-----------ANLKTVKAA--KLDAEEQTTIAKLGLELC---L 559

  Fly   709 LT--FDSEVAKWDDTGNDIIFLAKHMCMIMMEMTDFTRGRGPLKTTMDVINAAKKISEAGTKLDK 771
            ||  .||||.:||:..::::.|.:.:..:...|..||||.|.||||.|:.:.|:.:|:.|.:|..
Zfish   560 LTSDVDSEVERWDEQDHEMVRLCQIISSMAYSMYLFTRGEGLLKTTSDLFHQAEVLSDQGLQLCP 624

  Fly   772 LTREIAEQCPESSTKKDLLAYLQRIALYCHQIQ------------ITSKVKADVQNISGELI--V 822
            :.:.::.|..:.. :..:::..::::..|.|:|            |..||.:.:||..|.||  |
Zfish   625 VLQSLSTQLLDED-RMLIISETEKLSSACQQLQACAKTPVQGKSAIFQKVDSSIQNTKGILILVV 688

  Fly   823 SGLDSATSLIQAAKNLMNAVVLTVKYSYVASTKYTRQGTVSSPI 866
            ..|.....||:..|:         :.|.:||.::.|:..:|:|:
Zfish   689 YLLPICNKLIRKCKS---------ERSCLASPQHWREKQLSAPV 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-Cat	NP_524219.1	Vinculin	87..877	CDD:395830	197/826 (24%)
ctnnal1	NP_001137526.1	Vinculin	77..>510	CDD:279395	136/562 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3681
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810