DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrm and Hepacam

DIOPT Version :9

Sequence 1:	NP_001246890.1	Gene:	nrm / 40515	FlyBaseID:	FBgn0262509	Length:	2192	Species:	Drosophila melanogaster
Sequence 2:	NP_780398.2	Gene:	Hepacam / 72927	MGIID:	1920177	Length:	418	Species:	Mus musculus

Alignment Length:	304	Identity:	71/304 - (23%)
Similarity:	115/304 - (37%)	Gaps:	77/304 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   575 LVHYEPGPAAL---------SHFPLV---AVKKKSVTFSCSVDD-------PGFPESNRFRWLRG 620
            |:|...|.:||         |..|:|   ..:.|.||...|:..       |.:  .:|.|....
Mouse    42 LIHGTVGKSALLSVQYSSTSSDKPVVKWQLKRDKPVTVVQSIGTEVIGTLRPDY--RDRIRLFEN 104

  Fly   621 GRGPLQDIVTKD---WTVE-PVGLDSRTNYSCYAYNEGGKGVMATVNLEVHAPPFFIKNLPPYTG 681
            |...|.|:...|   :.|| .:..|:.|         |.|.:..||::.:..|...:.:    |.
Mouse   105 GSLLLSDLQLADEGTYEVEISITDDTFT---------GEKTINLTVDVPISRPQVLVAS----TT 156

  Fly   682 ILHSSPNATLTCRIECVPRCDISWQKDGVPIERNDSRYFIK--EKYMDASPATGDFESMLSVLHF 744
            :|..|...||.|..|...:...:|.|||.|: .||||..:.  :|.:..:....:.:.:.|.:..
Mouse   157 VLELSEAFTLNCSHENGTKPSYTWLKDGKPL-LNDSRMLLSPDQKVLTITRVLMEDDDLYSCVVE 220

  Fly   745 NMPNWPDS-------KFNIEADNANYSCVSTGNIV------------GGSIRSR------TYFGI 784
            |    |.|       |..:...::.|..:|||.|.            ..|.:||      ....:
Mouse   221 N----PISQVRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACWKPSKKSRKKRKLEKQNSL 281

  Fly   785 EYAPENTTVSENIVYVQEDTIPGRVICKSRANPEPSYKWIFKNE 828
            ||..:|    ::.:..:.||:| |...:.|.||...|  |.|::
Mouse   282 EYMDQN----DDRLKSEADTLP-RSGEQERKNPMALY--ILKDK 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrm	NP_001246890.1	Ig	44..152	CDD:299845
		Ig	176..248	CDD:299845
		Ig	277..354	CDD:299845
		IG_like	383..463	CDD:214653
		Ig	394..463	CDD:143165
		Ig_3	585..652	CDD:290638	19/89 (21%)
		Ig	685..>719	CDD:299845	13/33 (39%)
		IG_like	788..869	CDD:214653	11/41 (27%)
		Ig	<811..869	CDD:299845	6/18 (33%)
Hepacam	NP_780398.2	V-set	41..141	CDD:311561	25/109 (23%)
		Ig	164..228	CDD:319273	18/68 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..418		13/55 (24%)
		GlyL_C	<324..383	CDD:331170
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000