DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrm and Sirpb3

DIOPT Version :9

Sequence 1:	NP_001246890.1	Gene:	nrm / 40515	FlyBaseID:	FBgn0262509	Length:	2192	Species:	Drosophila melanogaster
Sequence 2:	XP_006235033.1	Gene:	Sirpb3 / 296149	RGDID:	1566226	Length:	487	Species:	Rattus norvegicus

Alignment Length:	417	Identity:	91/417 - (21%)
Similarity:	151/417 - (36%)	Gaps:	111/417 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 VILDAKGDRIKNGSVV------GPMQERQSLKATCTVRNTRPQPEVSWFRGTKRLTTYSPTHDLV 217
            :.|.....|:.:.::|      ||...|..              .|||.:.:......:|....|
  Rat    37 ISLKGPDHRVTSSNLVQFLCTAGPFSSRNL--------------SVSWLKNSNEHPASAPQLVPV 87

  Fly   218 DGLYTSTLELDW-TLSREDLAQDIECRVKSAAIQ---NVTVTKFSVDLQVRPT---SIDINGVKH 275
            :....|.....| .|:::|:...|.|:|....|.   .:|:....| ::|.||   :.:...::.
  Rat    88 NNHSYSVTSKAWVALTKQDILSQITCKVTHGDIDEPLRMTINLSQV-VRVTPTLKITTEPPEIQD 151

  Fly   276 HTVQGSKVVLTCDIHGARPA-VNLTWYNTTTIISSGENEITEVRSKSLEKSDGTF---HT-QSEL 335
            |..|  :|.|||.:....|. :.|.|      ..:|...:|...:::...||||:   || |.:.
  Rat   152 HAHQ--RVNLTCHVSNFYPQNMRLIW------AKNGHKILTVEHTQATRNSDGTYSVQHTLQEDA 208

  Fly   336 IFNATRF-----ENDRVFRCEAENIVLQINREKPISSALTLEV-------------LYPPVVKVS 382
            |.|.|.|     ::|                :.|:..::||..             |..|:.:.:
  Rat   209 ILNETNFICWVIQDD----------------QPPVRDSITLGTPRKVRGRKDYSHNLEGPLQRFA 257

  Fly   383 PSA---ITANTSEIVLLNCEYFANPASLTQVEWYRNDILVNVNDTTHYKGGNSENV-ALVIKSTE 443
            |.|   :...:||:          |.....|.|.:|:..:....|..:.||.:.|| :.|:...|
  Rat   258 PGASIQLKYTSSEL----------PTRQVTVIWLKNNHSLLQTQTNVFSGGETYNVTSTVLVPLE 312

  Fly   444 KEDIGNYSCQLSNNIGKGTSDQKINLDVQYAPTVEILMIPEGPVKESDESN----VTLFCNVLDA 504
            .:||.:....|..:.......:.|.|| ||      |.:|.. |:.|..|.    ||:.|:|
  Rat   313 SDDILSLVLCLVEHKSLVVFQKVIYLD-QY------LYVPPA-VRVSQSSTVSSLVTVTCHV--- 366

  Fly   505 NPSVLTKVRWYANSTLLKELPDCEETR 531
                   .|:|.....|..|.||...|
  Rat   367 -------ERFYPKDICLTWLEDCHVIR 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrm	NP_001246890.1	Ig	44..152	CDD:299845
		Ig	176..248	CDD:299845	14/72 (19%)
		Ig	277..354	CDD:299845	22/86 (26%)
		IG_like	383..463	CDD:214653	18/83 (22%)
		Ig	394..463	CDD:143165	14/69 (20%)
		Ig_3	585..652	CDD:290638
		Ig	685..>719	CDD:299845
		IG_like	788..869	CDD:214653
		Ig	<811..869	CDD:299845
Sirpb3	XP_006235033.1	Ig	34..138	CDD:299845	22/115 (19%)
		IgC	146..219	CDD:143166	22/80 (28%)
		Ig	251..346	CDD:299845	25/111 (23%)
		IgC	348..430	CDD:143166	14/49 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000