DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment nrm and si:ch211-74m13.1

DIOPT Version :9

Sequence 1:	NP_001246890.1	Gene:	nrm / 40515	FlyBaseID:	FBgn0262509	Length:	2192	Species:	Drosophila melanogaster
Sequence 2:	XP_001922015.4	Gene:	si:ch211-74m13.1 / 100149459	ZFINID:	ZDB-GENE-081104-12	Length:	328	Species:	Danio rerio

Alignment Length:	306	Identity:	75/306 - (24%)
Similarity:	121/306 - (39%)	Gaps:	78/306 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 ATCTVRNTRPQPEVSWFRGTKRLTTYSPTHD------LVDGLYTSTLEL---------DWTLSRE 234
            |.|.::...|:..|.:..........|.|||      .|.|:..|...|         ||.:...
Zfish    23 AECPLQINPPKLVVRFNSSASANCNTSVTHDGMGWEATVGGVPLSKANLITWRVSQLTDWKIEPP 87

  Fly   235 --DLAQDIECRVKSAAIQNVTVTKFSVDLQVRPTSIDINGVKHHTVQGSKVVLTCDIHGARPAVN 297
              .:....:|.|...    ||:.|       .|.|:.|:.|.....:|::..|.||||...||.|
Zfish    88 FCYINYGKQCEVPLP----VTIYK-------TPDSVSISTVNQIMTEGNQYELQCDIHNVAPAQN 141

  Fly   298 LT--WYNTTTIISSGENEITEVRSKSLEKSDGTFHTQS------ELIFNATRFENDRVFRCEAEN 354
            ||  ||...|:::               :::.|.:|:|      .|:.:..|.::...:|||.|
Zfish   142 LTINWYKGETLVN---------------QTNFTDNTKSPVNKIIRLLIHPDRADDGAQYRCETE- 190

  Fly   355 IVLQINREKP------ISSALTLEVLYPPVVKVSPSAITANTSEIVLLNCEYFANPASLTQVEWY 413
              |.:..|.|      .|..|:::|.|.|  :.|.||...:.|:.|.|||...||||::  ..|:
Zfish   191 --LNLGVEGPQPPPKNTSKPLSIDVHYKP--QHSSSAENISQSDTVYLNCTVKANPAAV--YTWH 249

  Fly   414 RNDILVNVNDTTHYKGGNSENVALVIKSTEKEDIGNYSCQLSNNIG 459
                      :.|.|    |.::..:..:.....|.|:|..:|::|
Zfish   250 ----------SEHLK----EKISSPVIQSSPLSPGKYTCTATNDLG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
nrm	NP_001246890.1	Ig	44..152	CDD:299845
		Ig	176..248	CDD:299845	16/79 (20%)
		Ig	277..354	CDD:299845	22/84 (26%)
		IG_like	383..463	CDD:214653	20/77 (26%)
		Ig	394..463	CDD:143165	17/66 (26%)
		Ig_3	585..652	CDD:290638
		Ig	685..>719	CDD:299845
		IG_like	788..869	CDD:214653
		Ig	<811..869	CDD:299845
si:ch211-74m13.1	XP_001922015.4	Ig2_ICAM-1_like	109..209	CDD:143232	31/117 (26%)
		Ig_2	217..281	CDD:290606	21/81 (26%)
		IG_like	230..281	CDD:214653	16/66 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910