DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mes2 and CG6163

DIOPT Version :9

Sequence 1:	NP_730768.1	Gene:	Mes2 / 40514	FlyBaseID:	FBgn0037207	Length:	437	Species:	Drosophila melanogaster
Sequence 2:	NP_001261709.1	Gene:	CG6163 / 39274	FlyBaseID:	FBgn0036155	Length:	428	Species:	Drosophila melanogaster

Alignment Length:	184	Identity:	41/184 - (22%)
Similarity:	72/184 - (39%)	Gaps:	34/184 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 APVS-GCLPTATH-------SLQDMSAAAAAIA-----LDMKPK--------------LEPHPLA 39
            |||: ..||||||       |...:..|....|     |..:|.              |.|.|..
  Fly   136 APVAPPPLPTATHGRGRPSGSFSWLQTATTPTAPQLPHLITQPPHSQGHGMTYTAFTGLVPPPAT 200

  Fly    40 AAT---AMPSQKIKKLVRRNASDKLKLIQMVHDNPILWDSRLPNFKGAEEEKNRA-WEHIGREFN 100
            .|:   |.|.:|:.:....:.|.:.::|..:...|.||..|..:.||..:.:..| |:....|..
  Fly   201 VASETVATPPRKLGRPSSLHNSMRGRIIDAIKTRPSLWAGRQRSEKGQGQSRTSAVWKEAAMEMG 265

  Fly   101 APGRRVARAFKSLRESYRREL---AHVKLMGNGFKPKWSLYEAMDFLRDVIRER 151
            .....:...:..:::.|..||   .|.:.....|:..|..::.|.|:|:::.::
  Fly   266 LTPTLMQTRWSIIKQRYVDELQKERHAQYSHQSFRSTWEHFDRMSFMREILLKK 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mes2	NP_730768.1	MADF	62..149	CDD:214738	19/90 (21%)
CG6163	NP_001261709.1	MADF	12..98	CDD:214738
CG6163	NP_001261709.1	MADF	226..316	CDD:214738	19/89 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438504
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930