DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BoYb and Ddx43

DIOPT Version :9

Sequence 1:	NP_649430.1	Gene:	BoYb / 40512	FlyBaseID:	FBgn0037205	Length:	1059	Species:	Drosophila melanogaster
Sequence 2:	XP_003750593.1	Gene:	Ddx43 / 682138	RGDID:	1586947	Length:	646	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	91/465 - (19%)
Similarity:	184/465 - (39%)	Gaps:	52/465 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DSYSGQNANRPLVATNCSEYAVAHANCQLRPVRRFAEV-SLLPDILETMRNLGLNRLLRLQSYTW 85
            |::..:|.|     ..|.:...........|:.:|.:. ...|:::|.::..|..:...:||..|
  Rat   212 DNWRKENFN-----ITCDDLKDGEKRPIPNPICKFEDAFHSYPEVMENIKRAGFQKPTPIQSQAW 271

  Fly    86 PHLAGGSGHGAMIVGSPASGRTFAYI-PPVCHAVSRALMDFTGQCEDVEHDISQPDRYGPIALIL 149
            |.:.  .|...:.|....:|:|.:|: |...|..|:.|              ::..|.||..|:|
  Rat   272 PIVL--QGIDLIGVAQTGTGKTLSYLMPGFIHLDSQPL--------------AREQRNGPGMLVL 320

  Fly   150 VPDLRRVHQVSAMCLALLRKAHKNDSVTLALNVSSTKSSQFFLKLLNGVGCLVATPAQLVWFWQE 214
            .|......||.|.|    .|....|..::.:.....:..| ...:..||..::|||.:|...  :
  Rat   321 TPTRELALQVEAEC----SKYSYGDLKSVCVYGGGDRDGQ-IQDVSKGVDIIIATPGRLNDL--Q 378

  Fly   215 APGLMRFPCLQFLVYDDVDLMSREQLQDVQQVLQEILPLSHSPQVVMVSKSYCHTLMSKLRAVND 279
            ....:....:.:||.|:.|.|.....:  .|:::.:|.:....|.:|.|.::.:.:....::...
  Rat   379 MNNFVNLKSVTYLVLDEADKMLDMGFE--PQIMKILLDVRPDRQTIMTSATWPYAVRRLAQSYLK 441

  Fly   280 KPALVFGDILEAALYGGTRIRISIMRSEAKANAVVQMLQQCSPEEFRTVIFCSDDGDMQCLVAAL 344
            :|.:|:...|:.......:..|.|...|.|...:...|:..||:: :.::|.|.......|.:.|
  Rat   442 EPMIVYVGTLDLVAVSTVKQNIIITTEEEKRTHIQTFLENMSPKD-KVIVFVSRKAVADHLSSDL 505

  Fly   345 EVQHYSCLPYYQTADLEVRQQVHSWQARSNGVILLCTDNCPE-LDIRDAHTIIHHSMSHSWSKFK 408
            .::|.|....:...:...|::...........||:.||.... ||:.|...:.::....:..::.
  Rat   506 ILRHISVESLHGNREQSDREKALENFKTGKVRILIATDLASRGLDVHDITHVYNYDFPRNIEEYV 570

  Fly   409 LRHLKISDNLCNMVKPTASIVKKPLYSLVLLDDNNHRQLPRLVDFLQ-LHQKVDHRLVEVAKR-- 470
            .|           |..|....:..: |:.|:..|:.|....|::.|: .:|.:...||.:|:|
  Rat   571 HR-----------VGRTGRAGRTGM-SITLITRNDWRIATELINILERANQNIPEELVLMAERYK 623

  Fly   471 ---IRQELGK 477
               :::|:.|
  Rat   624 ANKLKREMEK 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BoYb	NP_649430.1	P-loop_NTPase	81..263	CDD:304359	41/182 (23%)
Ddx43	XP_003750593.1	KH-I	68..133	CDD:412160
Ddx43	XP_003750593.1	PTZ00110	153..642	CDD:240273	91/465 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910