DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BoYb and AgaP_AGAP004351

DIOPT Version :9

Sequence 1:	NP_649430.1	Gene:	BoYb / 40512	FlyBaseID:	FBgn0037205	Length:	1059	Species:	Drosophila melanogaster
Sequence 2:	XP_001688456.2	Gene:	AgaP_AGAP004351 / 5667412	VectorBaseID:	AGAP004351	Length:	713	Species:	Anopheles gambiae

Alignment Length:	425	Identity:	93/425 - (21%)
Similarity:	165/425 - (38%)	Gaps:	99/425 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EKTWQSSRDSVYEVGDSYSGQNANRPLVATNCSEYAVAHANCQLRPVRRFAEVSLLPDILETMRN 71
            |:|::..:|            |..:| :....||:..|           |.|   .||::|.:|.
Mosquito   286 ERTFKDEKD------------NERKP-IPNPVSEFHQA-----------FGE---YPDLMEELRK 323

  Fly    72 LGLNRLLRLQSYTWPHLAGGSGHGAMIVGSPASGRTFAYIPPVCHAVSRALMDFTGQCEDVEHDI 136
            ........:|:..||.|.  .|...:.:....:|:|.|::.|       ||:...||      .|
Mosquito   324 QKFTTPTPIQAQAWPILL--RGEDLIGIAQTGTGKTLAFLLP-------ALIHIEGQ------PI 373

  Fly   137 SQPDRYGPIALILVPDLRRVHQ------------VSAMCLALLRKAHKNDSVTLALNVSSTKSSQ 189
            .:.:|.||..|:|.|......|            :.|:||      :........:||
Mosquito   374 PRGERGGPNVLVLAPTRELALQIEKEVAKYQFRGIKAVCL------YGGGDRRAQINV------- 425

  Fly   190 FFLKLLNGVGCLVATPAQLVWFWQEAPGLMRFPCLQFLVYDDVDLM--------SREQLQDVQQV 246
                :.|||..|:|||.:|....||  |::....:.:|:.|:.|.|        .|:.|.||:..
Mosquito   426 ----VRNGVEILIATPGRLNDLVQE--GVVDVSTITYLILDEADRMLDMGFEPQIRKVLLDVRPD 484

  Fly   247 LQEILPLSHSPQ-VVMVSKSYCHTLMSKLRAVNDKPALVFGDILEAALYGGTRIRISIMRSEAKA 310
            .|.::..:..|. |..:::||.|          |...:..|.:..||.:..|:: |.:|..|.|.
Mosquito   485 RQTVMTSATWPDGVRRLAQSYMH----------DPIQVYIGTLDLAATHTVTQV-IEVMDEEDKF 538

  Fly   311 NAVVQMLQQCSPEEFRTVIFCSDDGDMQCLVAALEVQHYSCLPYYQTADLEVRQQVHSWQARSNG 375
            ..:.:.::...|.: :.:|||........|.:...:.:.||...:...:...|:|  :.:...||
Mosquito   539 QRINEFVRDMQPTD-KVIIFCGKKTRADDLSSEFILSNISCQAIHGNREQSDREQ--ALEDIKNG 600

  Fly   376 V--ILLCTDNCPE-LDIRDAHTIIHHSMSHSWSKF 407
            .  ||:.||.... |||.|...::::....:..::
Mosquito   601 TVKILIATDVASRGLDIEDITHVVNYDFPRNIEEY 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BoYb	NP_649430.1	P-loop_NTPase	81..263	CDD:304359	48/202 (24%)
AgaP_AGAP004351	XP_001688456.2	KH-I	62..124	CDD:238053
		DEADc	315..512	CDD:238167	56/240 (23%)
		PTZ00424	316..683	CDD:185609	82/368 (22%)
		HELICc	534..654	CDD:238034	21/105 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910