DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BoYb and AgaP_AGAP004912

DIOPT Version :9

Sequence 1:	NP_649430.1	Gene:	BoYb / 40512	FlyBaseID:	FBgn0037205	Length:	1059	Species:	Drosophila melanogaster
Sequence 2:	XP_315003.3	Gene:	AgaP_AGAP004912 / 1275719	VectorBaseID:	AGAP004912	Length:	705	Species:	Anopheles gambiae

Alignment Length:	431	Identity:	96/431 - (22%)
Similarity:	171/431 - (39%)	Gaps:	59/431 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PVRRFAEVSLLPDILETMRNLGLNRLLRLQSYTWPHLAGGSGHGAMIVGSPASGRTFAYIPPVCH 116
            |:..|.|......:|:..:.........:|:..|.  ...||...:.:....||:|.|||.|
Mosquito   102 PIMHFHESGFPQYMLDEFQRQAFKEPTFIQAVGWS--IAMSGRDMVGIAKTGSGKTLAYILP--- 161

  Fly   117 AVSRALMDFTGQCEDVEHDISQPDRYGPIALILVPDLRRVHQVSAMCLALLRKAHKNDSVTLALN 181
                ||:..:.|......|       |||||:|.|......|:..:|          |.....:.
Mosquito   162 ----ALVHISNQPRIARGD-------GPIALVLAPTRELAQQIKQVC----------DDFGRRMG 205

  Fly   182 VSST----KSSQFFLK--LLNGVGCLVATPAQLVWFWQ-EAPGLMRFPCLQFLVYDDVDLMSREQ 239
            :.:|    .:|::..:  |..||..::|||.:|:.|.: |...|.|  | .:||.|:.|.|....
Mosquito   206 IYNTCVFGGASKYPQESDLRRGVEIVIATPGRLIDFLERETTNLRR--C-TYLVLDEADRMLDMG 267

  Fly   240 LQ-DVQQVLQEILPLSHSPQVVMVSKSYCHTLMSKL--RAVNDKPALVFGDILEAALYGGTRIRI 301
            .: .:::::.:|.|   ..||:|.|.::...: .||  ..:.|...:..|.:..||.....:| |
Mosquito   268 FEPQIRKIISQIRP---DRQVLMWSATWPKEI-RKLAEEFLRDYIQINIGSLNLAANENILQI-I 327

  Fly   302 SIMRSEAKANAVVQMLQQCSPE-EFRTVIFCSDDGDMQCLVAALEVQHYSCLPYYQTADLEVRQQ 365
            .......|.|.:.::|:|.|.: :.:|:||......:..:|..:..|.:.....:.....:.|..
Mosquito   328 DCCEEYEKENRLFKLLEQISSQNDGKTIIFVETKRKVDKIVNVIRRQGWRADGIHGDKSQKDRDY 392

  Fly   366 VHSWQARSNGVILLCTDNCPE-LDIRDAHTIIHHSMSHSWSKFKLRHLKISDNLCNMVKPTASIV 429
            |.:...||...||:.||.... ||:.|...:|:....::           :::..:.:..|....
Mosquito   393 VLNTFRRSTNGILVATDVASRGLDVDDVKFVINFDFPNN-----------TEDYVHRIGRTGRST 446

  Fly   430 KKPLYSLVLLDDNNHRQLPRLVDFLQ-LHQKVDHRLVEVAK 469
            .|.. |.......|..:.|.|:..|| .:|.::..|.|.|:
Mosquito   447 NKGT-SYTFFTPANSSKAPDLITVLQDANQYINPELHEYAR 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BoYb	NP_649430.1	P-loop_NTPase	81..263	CDD:304359	49/189 (26%)
AgaP_AGAP004912	XP_315003.3	DEADc	106..311	CDD:238167	56/237 (24%)
		DEXDc	119..326	CDD:214692	56/239 (23%)
		HELICc	322..454	CDD:238034	27/144 (19%)
		CTD	561..692	CDD:215026
		Dscam_C	591..>649	CDD:289151
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910