DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and TAT2

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_014622.1	Gene:	TAT2 / 854139	SGDID:	S000005380	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	485	Identity:	99/485 - (20%)
Similarity:	198/485 - (40%)	Gaps:	101/485 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGP-AVTISFLIAA--IASAFAGICYAEF 82
            |.|.|.|....|..:.:|.::|.|::|.:|: |....|| .|.|.:.||.  |.....|:  .|.
Yeast    76 SNLKRTLKPRHLIMIAIGGSIGTGLFVGSGK-AIAEGGPLGVVIGWAIAGSQIIGTIHGL--GEI 137

  Fly    83 AARVPKAGSAYVYSYVTIGEFVAFTIGWNLILE--YVIGTASVARGLS-GYFDSLINNNMSKALN 144
            ..|.|..|:...|....:...::|.:....:|:  :|:....:|..:: .|::|.|:..:..|:.
Yeast   138 TVRFPVVGAFANYGTRFLDPSISFVVSTIYVLQWFFVLPLEIIAAAMTVQYWNSSIDPVIWVAIF 202

  Fly   145 ESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLN-NIFTTVNLVTIAIVLVAGA----- 203
            .::.:.::..|                :..||..|.:|.. ...|....:.:.:||:.|.
Yeast   203 YAVIVSINLFG----------------VRGFGEAEFAFSTIKAITVCGFIILCVVLICGGGPDHE 251

  Fly   204 -MNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFD--CIATTGEEAINPKRN 265
             :.|..  |..|           |.:..|..||::......|...|.:  |:| :||  .:|| .
Yeast   252 FIGAKY--WHDP-----------GCLANGFPGVLSVLVVASYSLGGIEMTCLA-SGE--TDPK-G 299

  Fly   266 IPLSIVVSLIIIFLSYFGVS-TVLTMMLPYYKQD-------KDAPFPHAFDSVEWYTIKWIVTI- 321
            :| |.:..:....|.:|.:| |::..::||..|:       .::||..|   ::.:.||.:.:|
Yeast   300 LP-SAIKQVFWRILFFFLISLTLVGFLVPYTNQNLLGGSSVDNSPFVIA---IKLHHIKALPSIV 360

  Fly   322 GAVFALCTSLLG--AMFPLPRILYAMGKDGIL---FKRLSTVNSYTKTPLLATIVSGIFASIMAM 381
            .||..:....:|  .:|...|.|.:|...|::   |..:....    .||:..:.:.:| .::|.
Yeast   361 NAVILISVLSVGNSCIFASSRTLCSMAHQGLIPWWFGYIDRAG----RPLVGIMANSLF-GLLAF 420

  Fly   382 LFNLDQLVDMMSIGTLLAYTIVAICV-------------LVLRYQDEEMTKLVSVKAPNVFRQFF 433
            |.....:.::.:  .|:|...:|.|:             |.::.|.:.:.:|..|.|..::
Yeast   421 LVKSGSMSEVFN--WLMAIAGLATCIVWLSINLSHIRFRLAMKAQGKSLDELEFVSAVGIW---- 479

  Fly   434 NGNSFREPNSMTSSITKVGIVVFAIFCLVW 463
             |:::       |::....|::...:|.:|
Yeast   480 -GSAY-------SALINCLILIAQFYCSLW 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	99/485 (20%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
TAT2	NP_014622.1	LysP	52..591	CDD:223903	99/485 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960