Protein Alignment slif and GNP1

DIOPT Version :10

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_010796.1
• Gene: GNP1 / 852121
• SGDID: S000002916
• Length: 663
• Species: Saccharomyces cerevisiae
• Alignment Length: 654
• Identity: 135/654 - (20%)
• Similarity: 234/654 - (35%)
• Gaps: 196/654 - (29%)

  Fly    10 RRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAF 74
            ::..::..:.:..|.:.:.......:.:|:.:|.|:.|...:| .|.|||...|      |..|.
Yeast   132 KQSPQEQEQKQENLKKSIKPRHTVMMSLGTGIGTGLLVGNSKV-LNNAGPGGLI------IGYAI 189

  Fly    75 AGIC-YAEFAARVPKAGS-AYVYSYVTIGEF-----------VAFTIGWNLILEYV------IGT 120
            .|.| |....|    .|. |.:||.: ||.|           :.|::.|...|:::      :.|
Yeast   190 MGSCVYCIIQA----CGELAVIYSDL-IGGFNTYPLFLVDPALGFSVAWLFCLQWLCVCPLELVT 249

  Fly   121 ASVARGLSGYFDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAK---ESSF 182
            ||:.   ..|:.:.:|                     ||.......:|:..|..||||   |:.|
Yeast   250 ASMT---IKYWTTSVN---------------------PDVFVVIFYVLIVVINVFGAKGYAEADF 290

  Fly   183 LNN---IFTTVNLVTIAIVLVAGAMNANVDN------WRIP---KKDVP-EGFGTGGFMPFGIAG 234
            ..|   |...|....:||::..|  .|..|.      ||.|   :.|.| :.|          .|
Yeast   291 FFNCCKILMIVGFFILAIIIDCG--GAGTDGYIGSKYWRDPGAFRGDTPIQRF----------KG 343

  Fly   235 VMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLS---IVVSLIIIFLSYFGVSTVLTMMLPYYK 296
            |:|......:.|...:.:|.|..|..||::.||.:   ::..::.:||:..   |::..::||..
Yeast   344 VVATFVTAAFAFGMSEQLAMTASEQSNPRKAIPSAAKKMIYRILFVFLASL---TLVGFLVPYTS 405

  Fly   297 QD---------KDAPFPHAFDSVEWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILF 352
            ..         |.:|:..|..|.....:...:....:.::.:...||.:...|||.::.|.|...
Yeast   406 DQLLGAAGSATKASPYVIAVSSHGVRVVPHFINAVILLSVLSVANGAFYTSSRILMSLAKQGNAP 470

  Fly   353 KRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLA-------YTIVAICVLVL 410
            |....::...: |..|.:||.:| .::|...:..:..|:.:  .|||       :|.:.||:..:
Yeast   471 KCFDYIDREGR-PAAAMLVSALF-GVIAFCASSKKEEDVFT--WLLAISGLSQLFTWITICLSHI 531

  Fly   411 RYQDEEMTKLVSVKAPNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLVWCSLQKVFDLDST 475
            |::          :|..|     .|.|..|    ....::||         ||.|..
Yeast   532 RFR----------RAMKV-----QGRSLGE----VGYKSQVG---------VWGSAY-------- 560

  Fly   476 GGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPF-----VPCLSVFANLYLMFQLDLNTW 535
                      |||:::..:|..         |.|.:.|.     :...|.|.|           :
Yeast   561 ----------AVLMMVLALIAQ---------FWVAIAPIGGGGKLSAQSFFEN-----------Y 595

  Fly   536 IRFLIWIVIGYVIYFCYGMRNSTQISRSR----SHAEVAASALQNQGQHVNPGFEPDYK--VENG 594
            :...|||.: |:.|..:....|..|...:    ||..:....|..|.       :.:||  :.||
Yeast   596 LAMPIWIAL-YIFYKVWKKDWSLFIPADKVDLVSHRNIFDEELLKQE-------DEEYKERLRNG 652

  Fly   595 GRPY 598
              ||
Yeast   653 --PY 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	123/605 (20%)
GNP1	NP_010796.1	2A0310	146..626	CDD:273334	124/601 (21%)