DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and CAT8

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_173155.1	Gene:	CAT8 / 838282	AraportID:	AT1G17120	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	156/550 - (28%)
Similarity:	274/550 - (49%)	Gaps:	54/550 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAFAGICYAEF 82
            |.|:.:.|.|..:||..|..||.:|.||:|:.||.|...|||||.:|:.|:.:::..:.:|||||
plant    76 ESENPMRRCLTWWDLLWLSFGSVVGSGVFVITGQEARVGAGPAVVLSYAISGVSALLSVLCYAEF 140

  Fly    83 AARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINNNMSKALNESM 147
            ...:|.||.::.|..|.:|:|:||....|::||.::|.|.:.|..|.|..||:.|:     ::..
plant   141 GVEIPVAGGSFSYLRVELGDFIAFIAAGNILLEAMVGAAGLGRSWSSYLASLVKND-----SDYF 200

  Fly   148 HIDVDFLG---DYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGAMNANVD 209
            .|.||...   |..|.::..::|:...|...|.|.:|:||.|.:.|.:..|..::|.|..::...
plant   201 RIKVDSFAKGFDLLDPVAVAVLLVANGIAMTGTKRTSWLNLITSMVTVCIIVFIVVVGFTHSKTS 265

  Fly   210 NWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLSIVVSL 274
            |.      ||       |.|:|..||:..||..::.:.|||.:|...||...|.|:||:.:|.|:
plant   266 NL------VP-------FFPYGAKGVVQSAAVVYWSYTGFDMVANMAEETEKPSRDIPIGLVGSM 317

  Fly   275 IIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTIKWIVTIGAVFALCTSLLGAMFPLP 339
            .:|.:.|..::..||||:.|.:.|.:|.:..||..:.....|::|.|.|:..:.||||.......
plant   318 SMITVVYCLMALALTMMVKYTEIDANAAYSVAFAQIGMKWAKYLVGICALKGMTTSLLVGSLGQA 382

  Fly   340 RILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTLLAYTIVA 404
            |....:.:..::....:.|:..|.||:.||::..|.:||::...:|:.|..:.|..||..:.:||
plant   383 RYTTQIARSHMIPPWFALVHPKTGTPIYATLLVTILSSIISFFTSLEVLSSVFSFATLFIFMLVA 447

  Fly   405 ICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFC-LVWCSLQK 468
            :.:||.||..:::|                              .:.|::.|..|. |:..|...
plant   448 VALLVRRYYVKDVT------------------------------PEAGLLKFLGFLFLIIASSIG 482

  Fly   469 VFDLDSTG--GIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLD 531
            |..|.::|  |.:|.::.|.:..:..:.:.:.|...:...:.|||||::|..|:..||:|:..|.
plant   483 VSALWNSGVKGWIAYTVTGVIWFIGTLGLALLPKYRVPKVWGVPLVPWLPSFSIAMNLFLIGSLG 547

  Fly   532 LNTWIRFLIWIVIGYVIYFCYGMRNSTQIS 561
            ...::||:|..::..:.|...|:..:..::
plant   548 YVAFLRFIICTMVMLLYYLFVGLHATYDVA 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	156/544 (29%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	16/49 (33%)
CAT8	NP_173155.1	2A0303	77..575	CDD:273330	155/545 (28%)
CAT8	NP_173155.1	AA_permease_C	523..573	CDD:290617	16/49 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880