DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and CAT3

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_198510.2	Gene:	CAT3 / 833664	AraportID:	AT5G36940	Length:	609	Species:	Arabidopsis thaliana

Alignment Length:	633	Identity:	213/633 - (33%)
Similarity:	330/633 - (52%)	Gaps:	101/633 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KALTRRKTEDVNEGES-------QLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTI 63
            ::|.|||..|.:.|::       |||:.|....|.|:|||||:|.|||:|.|.||...:|||:.:
plant     5 RSLVRRKQFDSSNGKAETHHHHQQLAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALAL 69

  Fly    64 SFLIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLS 128
            |||||.|::|.:..||||.::|.|.|||||.|||:.|||.||:.|||.|||||.||.::||||:|
plant    70 SFLIAGISAALSAFCYAELSSRFPSAGSAYHYSYICIGEGVAWLIGWALILEYTIGGSTVARGIS 134

  Fly   129 GYFDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLV 193
            .....:...........:.| .:..|....|..:..:|.::..:...|.|||:|...|.||.|:.
plant   135 PNLAMIFGGEDCLPTILARH-QIPGLDIVVDPCAAVLVFIVTGLCCLGVKESTFAQGIVTTANVF 198

  Fly   194 TIAIVLVAGAMNANVDNW---RIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATT 255
            .:..|:|||:.......|   .:|.          |:.|:|:.|::.|:|..|:.::|||.:|:.
plant   199 VMIFVIVAGSYLCFKTGWVGYELPT----------GYFPYGVDGMLTGSATVFFAYIGFDTVASM 253

  Fly   256 GEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDS--VEWYTIKWI 318
            .||..||:|::||.|.:||::..|.|..||.|:..::|||..|.|.|...||.|  ::|  ..::
plant   254 AEEVKNPRRDLPLGIGISLLLCCLLYMMVSVVIVGLVPYYAMDPDTPISSAFSSHGIQW--AAYL 316

  Fly   319 VTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLF 383
            :.:|||.|||::|:|::.|.||||.||.:||:|....|.||..|:.|:..||.:|:.|:|:|...
plant   317 INLGAVMALCSALMGSILPQPRILMAMARDGLLPSYFSYVNQRTQVPINGTITTGVCAAILAFFM 381

  Fly   384 NLDQLVDMMSIGTLLAYTIVAICVLVLRY---QDEEMTKLVSVKAPNVFRQFFN---GNSFREPN 442
            ::.||..|:|:|||:|:|:|||.:|::||   .||       |..|:..::..:   |.|.|...
plant   382 DVSQLAGMVSVGTLVAFTMVAISLLIVRYVVPPDE-------VPLPSSLQENSSSHVGTSIRSKQ 439

  Fly   443 SMTSSI-------------------------------TKVG--IVVFAIFCLVWCSLQKVFDLDS 474
            .:...:                               |.:|  ::.:|....:...|.: :.|..
plant   440 PLLGKVDDSVVDKENAPGSWVLNKKNRRKFAGWSIMFTCIGNFLLSYAASSFLLPGLLR-YSLCG 503

  Fly   475 TGGIVALSLVGAVLILICV-------VIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDL 532
            .||:  ..||| :::|||:       ..|...      .|..|.||.:|.:.:..|:||:..|..
plant   504 VGGL--FLLVG-LIVLICIDQDDARHSFGHSG------GFICPFVPLLPIVCILINMYLLVNLGA 559

  Fly   533 NTWIRFLIWIVIGYVIYFCYGMRNST-------------QISRSRSHA 567
            .||:|..:|:.:|.|:|..||.|||:             :|.|:..|:
plant   560 ATWVRVSVWLFLGVVVYIFYGRRNSSLVNAVYVSTAHLQEIRRTSGHS 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	208/606 (34%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	19/49 (39%)
CAT3	NP_198510.2	2A0303	5..584	CDD:273330	208/608 (34%)
CAT3	NP_198510.2	AA_permease_C	534..584	CDD:290617	19/49 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840