DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and CAT6

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_196097.1	Gene:	CAT6 / 830355	AraportID:	AT5G04770	Length:	583	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	179/577 - (31%)
Similarity:	293/577 - (50%)	Gaps:	71/577 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAFAGICYAEFA 83
            || |:.|.|..:||..||:|..:|.||:|..|:.:...|||::.:|:.||.:.:..:..||.|||
plant    54 GE-QMRRTLRWYDLIGLGIGGMVGAGVFVTTGRASRLDAGPSIVVSYAIAGLCALLSAFCYTEFA 117

  Fly    84 ARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDS----------LINNN 138
            ..:|.||.|:.|..:|.|||.||..|.||:::||:..|:|:|..:.|..:          .:.:.
plant   118 VHLPVAGGAFSYIRITFGEFPAFFTGANLVMDYVMSNAAVSRSFTAYLGTAFGISTSKWRFVVSG 182

  Fly   139 MSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGA 203
            :.|..||.            |.::..:||::..|:....:|||.:|.|.|..::..|..|:|.|.
plant   183 LPKGFNEI------------DPVAVLVVLVITVIICCSTRESSKVNMIMTAFHIAFIFFVIVMGF 235

  Fly   204 MNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPL 268
            :..:..|...|..  ||  ...||.|||.|||..|||..:..::|:|.::|..||..||.::||:
plant   236 IKGDSKNLSSPAN--PE--HPSGFFPFGAAGVFNGAAMVYLSYIGYDAVSTMAEEVENPVKDIPV 296

  Fly   269 SIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAF-DSVEWYTIKWIVTIGAVFALCTSLL 332
            .:..|:.|:.:.|..::..::|:|||...|.:|||..|| .|..|..:..:|.|||.|.:.||||
plant   297 GVSGSVAIVTVLYCLMAVSMSMLLPYDLIDPEAPFSAAFRGSNGWEWVTKVVGIGASFGILTSLL 361

  Fly   333 GAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTL 397
            .||....|.:..:|:..::....:.::..|.||:.|:...|||.:.:|:..:|:.|::::|||||
plant   362 VAMLGQARYMCVIGRSRVVPFWFAKIHPKTSTPVNASTFLGIFTAALALFTDLNVLLNLVSIGTL 426

  Fly   398 LAYTIVAICVLVLRYQDEEMTKLVSVKAPNV-FRQFFNGNSFREPNSMTSSITKVGIVVFAIFCL 461
            ..:.:||..::..||.....||    ..|.: |...|             |||.:      :|.|
plant   427 FVFYMVANALIFRRYVPVGPTK----PWPTLCFLTLF-------------SITSL------VFTL 468

  Fly   462 VWCSL----QKVFDLDSTGGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFA 522
            :|..:    .|.|.|.:: .:||:::   ||...|||    |.:.....:.||.:|:.||:|:|.
plant   469 IWKLVPEGKPKAFMLGAS-AVVAIAI---VLSFQCVV----PQARKPELWGVPFMPWTPCVSIFL 525

  Fly   523 NLYLMFQLDLNTWIRFLIWIVIGYVIYFCYGMRNSTQISRSRSHAEVAASALQNQGQ 579
            |::|:..||..:::||..:..:..::|..||:..|       |.||...|.....||
plant   526 NIFLLGSLDAPSYVRFGFFSGLIVLVYLFYGVHAS-------SDAEANGSFGVKDGQ 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	172/553 (31%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	16/49 (33%)
CAT6	NP_196097.1	2A0303	51..562	CDD:273330	173/562 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880