DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and CAT7

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_187671.1	Gene:	CAT7 / 820229	AraportID:	AT3G10600	Length:	584	Species:	Arabidopsis thaliana

Alignment Length:	557	Identity:	176/557 - (31%)
Similarity:	288/557 - (51%)	Gaps:	81/557 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIASAFAGICYAEFA 83
            || |:.|.|..:||..||:|..:|.||:|..|:.:...|||::.:|:.||.:.:..:..||.|||
plant    53 GE-QMRRTLRWYDLIGLGIGGMIGAGVFVTTGRASRLYAGPSIVVSYAIAGLCALLSAFCYTEFA 116

  Fly    84 ARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDS----------LINNN 138
            ..:|.||.|:.|..:|.|||.||..|.|||::||:..|:|:||.:.|..|          .|.:.
plant   117 VHLPVAGGAFSYIRITFGEFPAFITGANLIMDYVLSNAAVSRGFTAYLGSAFGISTSEWRFIVSG 181

  Fly   139 MSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGA 203
            :....||.            |.::..:||.:..::.:..:|||.:|.:.|.:::..|..|:|.|.
plant   182 LPNGFNEI------------DPIAVIVVLAVTFVICYSTRESSKVNMVLTALHIAFIVFVIVMGF 234

  Fly   204 MNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPL 268
            ...:|.|  :.:.|.||  ...||.|||::||..|||..:..::|:|.::|..||..:|.::||:
plant   235 SKGDVKN--LTRPDNPE--NPSGFFPFGVSGVFNGAAMVYLSYIGYDAVSTMAEEVKDPVKDIPM 295

  Fly   269 SIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVE-WYTIKWIVTIGAVFALCTSLL 332
            .|..|:.|:.:.|..::..::|:|||...|.:||:..||...| |..:..:|.|||.|.:.|||:
plant   296 GISGSVAIVIVLYCLMAISMSMLLPYDLIDAEAPYSAAFSKSEGWEWVTRVVGIGASFGILTSLI 360

  Fly   333 GAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIGTL 397
            .||....|.:..:|:..::....:.|:..|.||:.|:...|||.:::|:..:|:.|::::|||||
plant   361 VAMLGQARYMCVIGRSRVVPIWFAKVHPKTSTPVNASAFLGIFTAVLALFTDLNVLLNLVSIGTL 425

  Fly   398 LAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNSFREPNSMTS-----SITKVGIVVFA 457
            ..:.:||..|:..||        |:|             .:.||....|     |||.:
plant   426 FVFYMVANAVIFRRY--------VTV-------------GYTEPWPTLSFLCLFSITSI------ 463

  Fly   458 IFCLVWCSLQKVFDLDSTG-------GIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFV 515
            :|.|||       .|..:|       |...::.:..|.|..|||    |.:.|...:.|||:|:.
plant   464 LFTLVW-------QLAPSGPPKWFILGASTVTAIAIVQIFHCVV----PQARIPEFWGVPLMPWT 517

  Fly   516 PCLSVFANLYLMFQLDLNTWIRFLIW---IVIGYVIY 549
            ||:|:|.|::|:..||..::|||..:   :|:.||.|
plant   518 PCVSIFLNIFLLGSLDAPSYIRFGFFSGLVVLVYVFY 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	176/557 (32%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	19/46 (41%)
CAT7	NP_187671.1	2A0303	50..561	CDD:273330	176/557 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880