DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and CAT5

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_181041.1	Gene:	CAT5 / 818060	AraportID:	AT2G34960	Length:	569	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	159/555 - (28%)
Similarity:	277/555 - (49%)	Gaps:	58/555 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 KTEDVNE-------GESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAA 69
            :::|.||       .|.::.|.|..:||...|.||.:|.|::||.||.|...||||:.:|::::.
plant    46 RSDDENERFELKKQSEHEMKRCLTWWDLVWFGFGSVIGAGIFVLTGQEAHEQAGPAIVLSYVVSG 110

  Fly    70 IASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSL 134
            :::..:..||.|||..:|.||.::.|..:.:|:|.||....|::||.::|||:|||..:.||.:|
plant   111 LSAMLSVFCYTEFAVEIPVAGGSFAYLRIELGDFAAFITAGNILLESIVGTAAVARAWTSYFATL 175

  Fly   135 INNNMSKALNESMHIDVDFLGDYP--DFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAI 197
            :|.:.:     ::.|..|....:.  |.::..::...|.|.:...:::|.||.|.:.:|.:.|..
plant   176 LNRSPN-----ALRIKTDLSSGFNLLDPIAVVVIAASATIASISTRKTSLLNWIASAINTLVIFF 235

  Fly   198 VLVAGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINP 262
            |::||.::|:..|.      .|       |:|||..||...||..::.:.|||.|||..||..||
plant   236 VIIAGFIHADTSNL------TP-------FLPFGPEGVFRAAAVVYFAYGGFDSIATMAEETKNP 287

  Fly   263 KRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTIKWIVTIGAVFAL 327
            .|:||:.::.|:.||.:.|..::..|:||..|...|.:|.:..||.||.....|::|.:||:..:
plant   288 SRDIPIGLLGSMSIITVIYCLMALSLSMMQKYTDIDPNAAYSVAFQSVGMKWGKYLVALGALKGM 352

  Fly   328 CTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMM 392
            .|.||.......|.:..:.:..::....:.|:..|.||:.|.::..|.::::|....||.|..::
plant   353 TTVLLVGALGQARYVTHIARTHMIPPIFALVHPKTGTPINANLLVAIPSALIAFFSGLDVLASLL 417

  Fly   393 SIGTLLAYTIVAICVLVLRY---QDEEMTKLVSVKAPNVFRQFFNGNSFREPNSMTSSITKVGIV 454
            ||.||..:|::.|.:||.||   ||.....|:.:....:|                       :|
plant   418 SISTLFIFTMMPIALLVRRYYVRQDTPRVHLIKLITCLLF-----------------------VV 459

  Fly   455 VFAIFCLVWCSLQKVFDLDSTGGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLS 519
            |.::....:..:|:..........|....:|.:.|:..|     |.......:.|||||::||||
plant   460 VSSMGTSAYWGMQRKGSWIGYTVTVPFWFLGTLGIVFFV-----PQQRTPKVWGVPLVPWLPCLS 519

  Fly   520 VFANLYLMFQLDLNTWIRFLIWIVIGYVIYFCYGM 554
            :..|::||..|....::||.:..:...:.||..|:
plant   520 IATNIFLMGSLGAMAFVRFGVCTLAMLLYYFLLGL 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	159/555 (29%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617	18/48 (38%)
CAT5	NP_181041.1	2A0303	54..559	CDD:273330	156/547 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880