Protein Alignment slif and slc7a4

DIOPT Version :9

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_919408.2
• Gene: slc7a4 / 796100
• ZFINID: ZDB-GENE-030919-2
• Length: 677
• Species: Danio rerio
• Alignment Length: 653
• Identity: 250/653 - (38%)
• Similarity: 357/653 - (54%)
• Gaps: 89/653 - (13%)

  Fly     8 LTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIAS 72
            |.|.||.|.:...:.|.|.||..||..||||..:|.|:|||.|.||.:.|||||.||||||.:||
Zfish    18 LNRLKTLDDDVMATSLKRCLNTVDLALLGVGGMVGSGLYVLTGTVAKDTAGPAVVISFLIAGVAS 82

  Fly    73 AFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINN 137
            ..|.:|||||.|||||.||||:::||::||..||.||||:||||:||.|:|||..|||.||:.|:
Zfish    83 LMAALCYAEFGARVPKTGSAYMFTYVSVGEIWAFLIGWNVILEYMIGGAAVARAWSGYLDSIFNH 147

  Fly   138 NMSKALNES--MHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLV 200
            .:.. ..||  |..:|.||..|||.|:..::|:.:..::||.:.||:||:||:.:::|.|..:||
Zfish   148 RIQN-FTESHVMRWEVPFLAHYPDLLAAAILLVASFFISFGVRVSSWLNHIFSAISMVVIVFILV 211

  Fly   201 AGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRN 265
            .|.:.|:..||...:         |||.|||::|:|||.|.|||.|||||.||.:.|||.||:|.
Zfish   212 FGFILADPVNWSARE---------GGFAPFGLSGIMAGTATCFYAFVGFDVIAASSEEASNPQRA 267

  Fly   266 IPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTIKWIVTIGAVFALCTS 330
            ||.:..:||.:...:|..||||||:|:|::..|.::....||....:....:||.:|::.|:.|.
Zfish   268 IPAATAISLGLAATAYVLVSTVLTLMVPWHTLDPNSALSDAFFRRGYSWAGFIVAVGSICAMNTV 332

  Fly   331 LLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMMSIG 395
            ||..:|.||||:|||.:||:.|...|.||..||.|::|.:|.|...:|:|::|:|:.||..:|||
Zfish   333 LLSNLFSLPRIVYAMAEDGLFFSVFSRVNPVTKVPVIAILVFGSLMAILALIFDLEALVQFLSIG 397

  Fly   396 TLLAYTIVAICVLVLRYQ--------------------------DEEMTKLVSVKAPNVFRQFFN 434
            ||||||.||..|:|||:|                          .::|...|:......|.|  :
Zfish   398 TLLAYTFVAASVIVLRFQPDKSSGSSGAGGVKTDASSTPSGNQSGQQMDLSVAANEAQTFAQ--D 460

  Fly   435 GNSFREPNSMTSSI-----TKVG----------------------------IVVFAIFCLV--WC 464
            |...:|..|.:..:     .|.|                            :|.|::..|:  ..
Zfish   461 GGELKEYESFSDKLQLVERQKAGKEKRAPGMLKARWEPYLGRLLGDCEPGEVVAFSVLALMVSGV 525

  Fly   465 SLQKV-------FDLDSTGGIVALSLVGAVLILICVVIGMQPVSTIELTFKVPLVPFVPCLSVFA 522
            ||..|       ..|......:.|.:...|.:|...:|.:........||:||||||:|..|:..
Zfish   526 SLSAVLVFGNNQLHLPVWSFTLLLVIFSVVFLLSLALISVHEQRPNLKTFQVPLVPFIPGFSILL 590

  Fly   523 NLYLMFQLDLNTWIRFLIWIVIGYVIYFCYGMRNSTQISRSRSHAEVAA-------SALQNQGQH 580
            |::||.:|...|||||.:|:..|.::||.||:.:|.:..|.:...:|||       .:|....|:
Zfish   591 NVFLMLKLSPLTWIRFTVWVAAGLLVYFGYGIWHSKEGLREQQGQDVAARYVVLPSGSLVETVQN 655

  Fly   581 VNP 583
            |.|
Zfish   656 VQP 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	241/618 (39%)
		AA_permease_C	507..557	CDD:290617	24/49 (49%)
slc7a4	NP_919408.2	2A0303	11..627	CDD:273330	242/620 (39%)
		AA_permease_C	575..625	CDD:290617	24/49 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.680