DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and slc7a4

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001072820.1	Gene:	slc7a4 / 780281	XenbaseID:	XB-GENE-960138	Length:	337	Species:	Xenopus tropicalis

Alignment Length:	320	Identity:	152/320 - (47%)
Similarity:	209/320 - (65%)	Gaps:	14/320 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIAAIAS 72
            |.|.||.:.:..|:.|.|.|:..|||.||||..:|.|:|||.|.||..||||||.||||||.:||
Frog    18 LNRVKTLEDDLMETSLKRCLSTIDLTLLGVGGMVGSGLYVLTGTVAKEIAGPAVIISFLIAGVAS 82

  Fly    73 AFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFDSLINN 137
            ..|.:|||||.|||||.||||:::||::||..||.||||:||||:||.|:|||..|||.||:.::
Frog    83 LLAALCYAEFGARVPKTGSAYMFTYVSVGEIWAFLIGWNVILEYMIGGAAVARAWSGYLDSMFDH 147

  Fly   138 NMSKALNESMHI---DVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVL 199
            .: |...|: |:   :|.||..|||||:.|::|:..|.::||.:.||:||:||..:::..|..:|
Frog   148 KI-KNYTET-HVGSWNVQFLAHYPDFLAAGILLVATAFISFGVRVSSWLNHIFAGISMGIILFIL 210

  Fly   200 VAGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKR 264
            :.|.:.|...||.      ||   .|||.|||.:|:|:|.|.|||.|||||.||.:.|||.||::
Frog   211 IFGFILAEPKNWG------PE---NGGFAPFGFSGIMSGTATCFYAFVGFDVIAASSEEAKNPQK 266

  Fly   265 NIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTIKWIVTIGAV 324
            .:|::..|||.:...:||.||||||:|:|:.....|:....||....:....:||..|::
Frog   267 AVPIATAVSLGLATAAYFLVSTVLTLMVPWNTLVPDSALSDAFYRRGYSWAGFIVAAGSI 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	152/320 (48%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
slc7a4	NP_001072820.1	AA_permease_2	11..>333	CDD:330980	152/320 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030