DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and slc7a7

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001032648.1	Gene:	slc7a7 / 641560	ZFINID:	ZDB-GENE-051127-5	Length:	501	Species:	Danio rerio

Alignment Length:	504	Identity:	118/504 - (23%)
Similarity:	206/504 - (40%)	Gaps:	108/504 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QLARVLNLFDLTALGVGSTLGLGVYVL-AGQVAFNIAGPAVTISFLIAAIASAFAGICYAEFAAR 85
            :|.:.::|.:...|.||:.:|.|::|. .|.:.::.:.....:.:.|..|.|.|..:||||....
Zfish    31 KLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSGSYGLSLVVWTIGGIFSVFGALCYAELGTT 95

  Fly    86 VPKAGSAYVYSYVTIGEFVAFTIGWN--LILEYVIGTASVARGLSGY-----FDSLINNNMSKAL 143
            :.|:|::|.|.....|.|:||...|.  ||:| ....|.:|...|.|     |.:.|...::..|
Zfish    96 ITKSGASYAYILEAFGGFLAFIRLWTSLLIIE-PTSQAVIAITFSNYMVQPIFPTCIAPYVANRL 159

  Fly   144 NESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGAM---N 205
                             |:...:.||..:.....|..:.:.:.||.|.:|.:..|::.|.:   .
Zfish   160 -----------------LAAACICLLTFVNCAYVKYGTRVQDFFTYVKVVALIAVIITGLVKIFQ 207

  Fly   206 ANVDNWRIPKKDVPEG-FGTGGFMPFGIAGVMAGAAKCFYGFVGFDCIATTGEEAINPKRNIPLS 269
            ....|:        || |......|..:|..:..|   .:.:.|:|.:....||..||:||:||:
Zfish   208 GYTQNF--------EGLFSDSSHDPGDVALALYSA---LFSYSGWDTLNFVTEEIKNPERNLPLA 261

  Fly   270 IVVSLIIIFLSYFGVSTVLTMMLPYYK-------QDKDAPFPHAFDSVEWYTIKWIVTIGAVFAL 327
            |.:|:.|:.:.|     :|| .|.||.       .|.||......|.|..| :.|.:.:...|:.
Zfish   262 IAISMPIVTVIY-----ILT-NLAYYTILPIPAILDSDAVAVTFADQVFGY-LNWTIPVAVAFSC 319

  Fly   328 CTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASIMAMLFNLDQLVDMM 392
            ...|..::....|:.:...::|.|...|..::....||            |.|:|||
Zfish   320 FGGLNASIVAASRLFFVGSREGHLPDYLCMIHITRFTP------------IPALLFN-------- 364

  Fly   393 SIGTLLAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNS--------FREPNSMTSSIT 449
              |   |..:|.:||       |::.||::..:.:.:  ||.|.|        :::|:....  .
Zfish   365 --G---AMALVYLCV-------EDVFKLINYYSFSYW--FFVGLSILGQLYLRWKQPDRPRP--L 413

  Fly   450 KVGIVVFAIFCLVWCSLQKVF------DLDSTGGIVALSLVGAVLILIC 492
            |:.:....||||  |::..|.      .::|..|| .::|.|..:..:|
Zfish   414 KLSLFFPIIFCL--CTVFLVVVPLYSDTINSLIGI-GIALPGVPVYFLC 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	118/504 (23%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
slc7a7	NP_001032648.1	2A0308	2..492	CDD:273332	118/504 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592986
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.850