DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and slc7a10a

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001373301.1	Gene:	slc7a10a / 567420	ZFINID:	ZDB-GENE-080116-1	Length:	511	Species:	Danio rerio

Alignment Length:	510	Identity:	106/510 - (20%)
Similarity:	205/510 - (40%)	Gaps:	77/510 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVL-------AGQVAFNIAGPAVTI 63
            |.|..|..:..::....|.:.:.|....|:.:|:.:|.|:::.       ||.|.|::      |
Zfish    18 KMLDSRGNQSGSKDRVTLKKEIGLLSACAIIIGNIIGSGIFISPKGVLDHAGSVGFSL------I 76

  Fly    64 SFLIAAIASAFAGICYAEFAARVPKAGSAYVYSYVT--IGEFVAFTIGWNLIL-EYVIGTASVAR 125
            .:::.....|...:||||....:||:|..  |||||  .|..|.|.:.|:.:| .|....|.:|.
Zfish    77 VWVLGGGICALGSLCYAELGVTIPKSGGD--YSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIAL 139

  Fly   126 GLSGY-----FDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNN 185
            ..|.|     |.:.:...::..|                 ||...||.|..:.....:..:.:.:
Zfish   140 TFSNYVLQPAFPNCLPPYIATRL-----------------LSTTCVLFLTWVNCSSVRWGTRIQD 187

  Fly   186 IFTTVNLVTIAIVLVAGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAGVMAGA-AKCFYGFVGF 249
            :||...|:.:.:::|.|.:.....::     |..|......|:.....|.:|.| .:..:.:.|:
Zfish   188 VFTVGKLLALVLIIVVGMVQIAKGHY-----DALEPQAAFEFIKDPSVGQIALAFLQASFAYSGW 247

  Fly   250 DCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVS-TVLTMMLPYYKQDKDAPFPHAFDSVEWY 313
            :.:....||.:.|::|:|.:|.:|:.::.|.|...: ...:.|.|....:.:| ....|......
Zfish   248 NFLNYVTEEVVEPRKNLPRAIYISIPLVTLVYTLTNIAYFSSMSPQELLESNA-VAVTFGEKLLG 311

  Fly   314 TIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASI 378
            ...|::.|....:....:.|.:|...|:.::..::|.|...|:.::..:.||:.|.||......:
Zfish   312 MFSWVMPISVALSTFGGINGYLFTSSRLCFSGAREGHLPYLLAMIHLKSCTPIPALIVCCTATIV 376

  Fly   379 MAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLVSVKAPNVFRQFFNGNSFREPNS 443
            :..:.:...|::.:|....|:|.:....:|..|:           |.||:||..
Zfish   377 ILCIGDTHNLINYVSFINYLSYGVTIAGLLYYRW-----------KKPNMFRPI----------- 419

  Fly   444 MTSSITKVGIVVFAIFCLVWCSLQKVFDLDSTGGIVALSLVGAVLILICVVIGMQ 498
                  ||.::|...:.:.|..|.. |.|.|...:..:.||..:..:....||:|
Zfish   420 ------KVNLLVPCSYLVFWAVLLG-FSLYSEPVVCGMGLVIMLTGVPIYFIGVQ 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	105/508 (21%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
slc7a10a	NP_001373301.1	2A0308	1..497	CDD:273332	106/510 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940