DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment slif and SLC7A10

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	XP_011525421.1	Gene:	SLC7A10 / 56301	HGNCID:	11058	Length:	660	Species:	Homo sapiens

Alignment Length:	358	Identity:	67/358 - (18%)
Similarity:	138/358 - (38%)	Gaps:	78/358 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 LARVLNLFDLTALGVGSTLGLGVYVL-------AGQVAFNIAGPAVTISFLIAAIASAFAGICYA 80
            |.:.:.|.....:.:|:.:|.|:::.       :|.|     |.|:.: :::....:|...:|||
Human    36 LKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSV-----GLALFV-WVLGGGVTALGSLCYA 94

  Fly    81 EFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLIL-EYVIGTASVARGLSGYFDSLINNNMSKALN 144
            |....:||:|..|.|.....|....|.:.|:.:| .|....|.::...|.|....:..|......
Human    95 ELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTT 159

  Fly   145 ESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAIVLVAGAMNANVD 209
            .|.            .||...::||..:.:...:.::.:.::||...|:.:::::..|.:.....
Human   160 ASR------------VLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQG 212

  Fly   210 NWRIPKKDVPEGFGTGGFMPFGIAGVMAGAAKCF----YGFVGFDCIATTGEEAINPKRNIPLSI 270
            ::        |.........|.:...:...|..|    :.|.|::.:....||.::.::|:|.:|
Human   213 HF--------EELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAI 269

  Fly   271 VVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEWYTI---KWIVTIGAVFALCTSLL 332
            .:|:.::                        .|.:.|.::.::|.   :.:::..||..:...||
Human   270 FISIPLV------------------------TFVYTFTNIAYFTAMSPQELLSSNAVAVVSGPLL 310

  Fly   333 GAMF---PLPR----ILYAMGKD------GILF 352
            |...   ||||    .||....|      |:||
Human   311 GPWLLPRPLPRPYTWPLYCAHPDLRGEAAGLLF 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	67/358 (19%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	67/358 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157258
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.850