DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slif and Slc7a5

DIOPT Version :9

Sequence 1:	NP_649428.1	Gene:	slif / 40510	FlyBaseID:	FBgn0037203	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_059049.1	Gene:	Slc7a5 / 50719	RGDID:	620639	Length:	512	Species:	Rattus norvegicus

Alignment Length:	439	Identity:	95/439 - (21%)
Similarity:	189/439 - (43%)	Gaps:	51/439 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KALTRRKTEDVN-EGES-QLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLIA 68
            |.|..|:.:..: |||. .|.|.:.|.:..|:.||:.:|.|::|....|......|.  :|.::.
  Rat    28 KMLEARRGDGADPEGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAGSPG--LSLVVW 90

  Fly    69 AIASAFA---GICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130
            |:...|:   .:||||....:.|:|..|.|.....|...||...|..:|        :.|..|.|
  Rat    91 AVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELL--------IIRPSSQY 147

  Fly   131 FDSLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTI 195
            ..:|:   .:..|.:.:........:....::...||||.|:..:..|.::.:.:.|....|:.:
  Rat   148 IVALV---FATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLAL 209

  Fly   196 AIVLVAGAMNANVDNWRIPKKDVPEGFGTGGFMPFGIAG-------VMAGAAKCFYGFVGFDCIA 253
            |::::.|.:...        ||:.:|..:.........|       ::.......:.:.|::.:.
  Rat   210 ALIILLGFIQMG--------KDIGQGDASNLHQKLSFEGTNLDVGNIVLALYSGLFAYGGWNYLN 266

  Fly   254 TTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVEW--Y--- 313
            ...||.|||.||:||:|::||.|:.|.|     |||.:..:.....:........:|::  |
  Rat   267 FVTEEMINPYRNLPLAIIISLPIVTLVY-----VLTNLAYFTTLSTNQMLTSEAVAVDFGNYHLG 326

  Fly   314 TIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFASI 378
            .:.||:.:....:...|:.|::|...|:.:...::|.|...||.::....||    :.|.:|..:
  Rat   327 VMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTP----VPSLVFTCV 387

  Fly   379 MAMLF----NLDQLVDMMSIGTLLAYTIVAICVLVLRYQDEEMTKLVSV 423
            |.:::    ::..:::..|....|...:..|.::.||::..|:.:.:.|
  Rat   388 MTLMYAFSRDIFSIINFFSFFNWLCVALAIIGMMWLRFKKPELERPIKV 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	94/437 (22%)
slif	NP_649428.1	AA_permease_C	507..557	CDD:290617
Slc7a5	NP_059049.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43		4/14 (29%)
Slc7a5	NP_059049.1	2A0308	23..511	CDD:273332	95/439 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351201
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940