Protein Alignment slif and slc7a2

DIOPT Version :9

• Sequence 1: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_001008584.1
• Gene: slc7a2 / 494041
• ZFINID: ZDB-GENE-041212-5
• Length: 640
• Species: Danio rerio
• Alignment Length: 639
• Identity: 296/639 - (46%)
• Similarity: 409/639 - (64%)
• Gaps: 69/639 - (10%)

  Fly     6 KALTRRKTEDVNEG---ESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISFLI 67
            ::|.|||  :|::|   ||:|.|.|:..||.|||||||||.|||||||:||...:||::.:||||
Zfish    10 RSLVRRK--NVDQGCLEESKLCRCLSTVDLIALGVGSTLGAGVYVLAGEVAKGSSGPSIVVSFLI 72

  Fly    68 AAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGYFD 132
            ||:||..||:|||||.|||||.||||:|||||:||..||..||||||.|||||:||||..||.||
Zfish    73 AALASVMAGLCYAEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFD 137

  Fly   133 SLINNNMSKALNESMHIDVDFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVTIAI 197
            .:|..::.|.......:.:..|.:||||.:..::|||:.:|:||.|||:::|.|||.||::.:..
Zfish   138 EIIGGHIEKFCKMYFKMSLPGLAEYPDFFAVCLILLLSGLLSFGVKESAWVNKIFTAVNVLVLMF 202

  Fly   198 VLVAGAMNANVDNWRIPKK----------------DVPEGFGTGGFMPFGIAGVMAGAAKCFYGF 246
            |:::|.:..:..||.|.::                :|...:|.|||.|:|..|.:||||.|||.|
Zfish   203 VIISGFVKGDSLNWNISEESLVNITVVKRNISSAANVTSDYGAGGFFPYGFGGTLAGAATCFYAF 267

  Fly   247 VGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSVE 311
            ||||||||||||..||:|.||:.|||||::.||:|||||..||:|:|||..|:.:|.|.||:.|.
Zfish   268 VGFDCIATTGEEVKNPQRAIPIGIVVSLLVCFLAYFGVSAALTLMMPYYLLDEKSPLPLAFEYVG 332

  Fly   312 WYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIFA 376
            |...|::|..|::.||.|||||:||||||||:||.:||:||:.||.: |..::|:.||:.:|..|
Zfish   333 WGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGVLFRFLSKL-SKRQSPVAATMAAGTTA 396

  Fly   377 SIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQ------------------DEEMTKLVSV 423
            :|||.||:|..|||||||||||||::||.|||:||||                  :.|:|:  |.
Zfish   397 AIMAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPDASFERSRISEGKEEVGESELTE--SE 459

  Fly   424 KAPNVFRQFFNGNSFRE-------PNSMTSSITKVGIVVFAIFCLVWCSL-----QKVFDLDSTG 476
            ...|:.:.  .|.:.|.       |...|||:..|.:::..:...|..:|     |.:..::...
Zfish   460 SHLNMLKD--GGVTLRSLLHPPLLPTENTSSVVNVSVIITVLVVCVVSTLNTYYGQAIIAMELWA 522

  Fly   477 -GIVALSLVGAVLILICV-VIGMQPVSTIELTFKVPLVPFVPCLSVFANLYLMFQLDLNTWIRFL 539
             |::|.||   .:.:||| :|..||.:..:::|.|||:||:|.||:|.|:|||.||..:|||||.
Zfish   523 LGVLAASL---FIFIICVFLICRQPQTRKKVSFMVPLLPFLPILSIFVNVYLMVQLSGDTWIRFS 584

  Fly   540 IWIVIGYVIYFCYGMRNSTQISRSRSHAEVAASALQNQGQHVNPGFEPDYKVEN 593
            ||:.||::|||.|||.:|.:..|   |.:..|.|.:.:....|.||     |||
Zfish   585 IWMAIGFLIYFGYGMWHSDERKR---HLQNCAVATEKKTLTGNEGF-----VEN 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slif	NP_649428.1	2A0303	8..557	CDD:273330	285/599 (48%)
		AA_permease_C	507..557	CDD:290617	31/49 (63%)
slc7a2	NP_001008584.1	2A0303	6..604	CDD:273330	286/603 (47%)
		AA_permease_C	552..602	CDD:290617	31/49 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593047
Domainoid	1	1.000	463	1.000	Domainoid score	I454
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	557	1.000	Inparanoid score	I1071
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm6524
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2006
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940